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Bioengineering
Combined treatment takes a bite out of tooth decay
A collaborative interdisciplinary team of researchers from Penn Dental, Medicine and Penn Engineering have discovered a game-changing synergy between ferumoxytol and stannous fluoride in treating dental caries.
Three from Penn receive NIH Director Award
Kevin B. Johnson, Jina Ko, and Sheila Shanmugan awarded NIH Common Fund’s High-Risk, High-Reward Research program.
Center for Innovation & Precision Dentistry positions Penn as a leader in engineering health
In the two years since the cross-disciplinary research partnership was founded, CiPD has introduced microrobots that clean teeth, a new understanding of bacterial physics in tooth decay, and promising futures for lipid nanoparticles in oral cancer treatment.
A suit of armor for cancer-fighting cells
New research from the University of Pennsylvania offers a safer path for CAR T cell immunotherapy.
A low-cost, eco-friendly COVID test
César de la Fuente and a team of Penn engineers work on creative ways to create faster and cheaper testing for COVID-19. Their latest innovation incorporates speed and cost-effectiveness with eco-friendly materials.
The physics of fat droplets reveal DNA danger
Penn Engineers are the first to discover fat-filled lipid droplets’ surprising capability to indent and puncture the nucleus, the organelle which contains and regulates a cell’s DNA.
For a new generation of antibiotics, scientists are bringing extinct molecules back to life
Marrying artificial intelligence with advanced experimental methods, Penn Engineering’s Machine Biology Group has mined the ancient past for future medical breakthroughs, bringing extinct molecules back to life.
SCALAR: A microchip designed to transform the production of mRNA therapeutics and vaccines
Researchers have developed a platform that could rapidly accelerate the development of mRNA-based lipid nanoparticle vaccines and therapeutics at both the small and largescale, SCALAR.
QR code for cancer cells
Researchers from Penn Engineering have created a new synthetic biology approach to uncover why some cells become resistant to anti-cancer therapies.
Holman Biotech Commons meets the evolving needs of campus
Resources at the Penn Libraries’ Holman Biotech Commons are available to the entire Penn community to support research, collaboration, and innovation.
In the News
Can your personal medical devices be recycled?
A lab at the School of Engineering and Applied Science led the development of a COVID test made from bacterial cellulose, an organic compound.
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Scientists think they’re on the verge of breaching the blood-brain barrier
Michael Mitchell of the School of Engineering and Applied Science and colleagues have constructed a model that could potentially allow drug transporters to bypass the blood-brain barrier.
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How severed cockroach legs could help us ‘fully rebuild’ human bodies
David Meaney of the School of Engineering and Applied Science oversees an undergraduate bioengineering lab that uses cockroach legs to teach students to work with human prostheses.
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Herniated discs could be repaired with biologic patch one day, researchers say
Preclinical research by Robert Mauck of the Perelman School of Medicine, Thomas Schaer of the School of Veterinary Medicine, and Ana Peredo, a Ph.D. graduate of the School of Engineering and Applied Science, reveals how a biologic patch activated by natural motion could become a key tool for repairing herniated discs in the back and relieving pain.
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Thanks, Neanderthals: How our ancient relatives could help find new antibiotics
A study by César de la Fuente of the Perelman School of Medicine and colleagues used AI to recreate molecules from ancient humans that could be potential candidates for antimicrobial treatments.
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Why CAR T cell therapy is the cancer killer the world needs now
Research from Michael Mitchell of the School of Engineering and Applied Science has developed a new method to stop cytokine release during CAR T cell therapy, preventing some of its more dangerous side effects.
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