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Perelman School of Medicine
Research shows how stress activates neurons that disrupt sleep
New research from Penn Medicine shows suppressing these neurons may be a promising target for therapies to treat stress-related sleep disorders, like insomnia and PTSD.
First in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses
The therapy tested in a Phase 1 clinical trial might drastically change the way the T cells work, potentially allowing the new CAR T cell product to work where other products have failed.
One in six patients with opioid use disorder leaving the hospital before completing treatment
A new Penn Medicine analysis shows that discharges too early for patients with opioid use disorder increased over 50% between 2016 and 2020.
Could a single shot heal heart disease?
Experts at Penn Medicine are researching novel treatments for heart disease, including CRISPR gene editing technology, CAR T technology, and mRNA injections.
Lidocaine may be able to kill certain cancer cells by activating bitter taste receptors
A preclinical Penn Medicine study explains the previously observed anti-cancer effect of the common anesthetic drug.
A space for lifesaving, collaborative work
Gov. Josh Shapiro, President Liz Magill, and others from the University community celebrated the new home of the Penn Institute for RNA Innovation.
From high school to the hospital
An immersive program at the Perelman School of Medicine gives high school students a sneak peek at a potential future in the medical field.
New ‘patch’ uses natural body motion to fix disc herniation
The tension-activated repair patch plugs holes in discs in the spine like car tire patches, and could prevent further disease progression.
Pain scores, age can help identify patients more likely to use few or no opioids after surgery
A Penn Medicine study shows that patient pain scores are a good predictor for opioid use, but younger patients and those who hadn’t used opioids before are less likely to take them.
Decentralizing cancer screenings
A Projects for Progress team in the Abramson Cancer Center continues to work with the West Philadelphia community to bring cancer screenings out of clinical settings.
In the News
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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