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Perelman School of Medicine
Penn Study Finds Genetic Mutations Linked With Ethnic Disparities in Cancer
One of the goals of genome sequencing is to identify genetic mutations associated with increased susceptibility to disease. Yet by and large these discoveries have been made in people of European or Asian ancestry, resulting in an incomplete picture of global genetic variation in disease vulnerability.
Penn Team Finds Ovarian Cancer Oncogene in 'Junk DNA'
Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease.
New Penn Integrates Knowledge Website Highlights Program’s Broad Impact
Since 2005 the University of Pennsylvania‘s Penn Integrates Knowledge program has brought to campus exceptional faculty members whose research and teaching exemplify the integration of knowledge across disciplines.
Penn Study Shows Better Outcomes for Sepsis Patients Treated in Hospitals with Higher Volume of Cases
Patients with sepsis, one of the most time-sensitive and hard-to-detect illnesses in medicine, are more likely to survive the life-threatening condition when treated at a hospital that sees a higher volume of sepsis cases.
Penn Medicine Study: Attacking a Rare Disease at its Source With Gene Therapy
Treating the rare disease MPS I is a challenge. MPS I, caused by the deficiency of a key enzyme called IDUA, eventually leads to the abnormal accumulation of certain molecules and cell death.
Drug for Rare Blood Disorder Developed at Penn Receives Orphan Drug Status from European Union
A Penn Medicine-developed drug has received orphan status in Europe this week for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis.
Penn Study Shows 25 Percent Fewer Opioid-Related Deaths in States Allowing Medical Marijuana
On average, states allowing the medical use of marijuana have lower rates of deaths resulting from opioid analgesic overdoses than states without such laws. Opioid analgesics, such as OxyContin, Percocet and Vicodin, are prescribed for moderate to severe pain, and work by suppressing a person’s perception of pain.
Penn Study: Electronic Alerts Significantly Reduce Catheter-Associated Urinary Tract Infections
A Penn Medicine team has found that targeted automated alerts in electronic health records significantly reduce urinary tract infections in hospital patients with urinary catheters. In addition, when the design of the alert was simplified, the rate of improvement dramatically increased.
Taking ‘The Condom Pledge’: Penn Student’s Project Leads to Global Changes
Jason Parad is changing lives, and he’s doing it with condoms.
Penn Engineering Postdoc Duygu Kuzum Is One of ‘Innovators Under 35’
By Madeleine Stone @themadstone
In the News
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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