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Penn researchers can predict 10-year breast cancer recurrence with MRI scans that characterize the genetic makeup of tumors, allowing for individualized, non-invasive treatment.
Adam Cohen of the Perelman School of Medicine headed a clinical trial that found an experimental therapy can make a difference for patients who have exhausted other options.
Immunotherapy is a “game changer” for improving outcomes in treating Glioblastoma Multiforme, the most common, and most lethal, malignant brain tumor in adults.
A team led by Rumela Chakrabarti of the School of Veterinary Medicine has made new discoveries into how a key protein involved in triple-negative breast cancer functions in puberty.
A Penn study shows the promise of an off-the-shelf immunotherapy in relapse/refractory non-Hodgkin lymphoma, even when CAR T therapy fails.
The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy.
A study from the Abramson Cancer Center finds that turning on a key metabolic process could make soft tissue sarcoma more susceptible to treatment.
Penn researchers are the first to assess Helicobacter pylori infection and gastric cancer risk among certain demographics and ethnic groups.
Genetically editing a cancer patient’s immune cells using CRISPR/Cas9 technology, then infusing those cells back into the patient appears safe and feasible based on early data from the first-ever clinical trial to test the approach in humans in the United States.
With CAR T cell therapy, a patient’s own immune cells are genetically modified and inserted back into the body to find and kill cancer. Now scientists have now discovered a new way to track CAR T cells in the body.
A 2020 study from the Perelman School of Medicine found that a blood test to screen for certain biomarkers associated with pancreatic cancer was 92% accurate in its ability to detect disease.
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A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.
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A trial led by Susan Domchek of the Perelman School of Medicine could use a preventive vaccine to protect people with a BRCA gene mutation from cancer.
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Penn Medicine researchers like Nobel laureate Drew Weissman are leading efforts to develop a vaccine that prevents cancer, with remarks from Susan Domchek of the Basser Center for BRCA and Robert H. Vonderheide of the Abramson Cancer Center.
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Daiwei Zhang and Mingyao Li of the Perelman School of Medicine and colleagues have developed an AI tool called iStar that can automatically spot tumors and types of cancer that are difficult for clinicians to see or identify and can predict candidates for immunotherapy.
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The Abramson Cancer Center is attempting to address one of the most common challenges cancer patients face: lack of transportation to critically important appointments. Robert Vonderheide and Carmen Guerra of the Perelman School of Medicine are quoted on the Ride Health initiative.
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