As long as humans have been alive, they’ve been seeking ways to extend life just a little longer. So far no one has found the fountain of youth, but researchers have begun to understand how humans age, little by little, offering hope for therapies that may blunt the effects of time on the body.

Katherine Unger Baillie ・September 25, 2014

Maintaining the ends of chromosomes, called telomeres, is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer.

Karen Kreeger ・September 25, 2014

“Knowledge is power” is an old saying. Another cliché warns, “a little knowledge is a dangerous thing.” When it comes to getting inoculated against the Human Papilloavirus (HPV), it seems that neither saying is true. In fact, according to a study by a multidisciplinary University of Pennsylvania research team, knowledge may in fact be a meaningless thing.

Joseph J. Diorio, Lee-Ann Donegan ・September 25, 2014

More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how these signals are controlled during tumor formation is not fully understood.

Karen Kreeger ・September 19, 2014

The John D. and Catherine T. MacArthur Foundation announced Wednesday that the University of Pennsylvania’s Danielle S. Bassett has been selected as a 2014 MacArthur Fellow.

Evan Lerner ・September 17, 2014

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.

Karen Kreeger ・September 11, 2014