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Getting to the root of root canals
Person receiving treatment in a dental clinic.

Image: Courtesy of Penn Dental Medicine/Peter Olson Photography

Getting to the root of root canals

Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.
Stentix wins the 2025 Y-Prize
Winners of Penn’s 2025 Y-Prize holding their certificates.

The Stentix team (top) Summer Cobb and Amanda Kossoff, (bottom) Aarsha Shah and Elizabeth Jia, with judges (descending left) Matt Fitz-Henry, Jason Smith, Jennifer Gilburg, and Sasha Schrode, and (descending right) David Hsu, Gerald Lopez, and Dean Miller.

(Image: Courtesy of the William and Phyllis Mack Institute for Innovation Management)

Stentix wins the 2025 Y-Prize

The winning team of Penn Engineering’s annual award for entrepreneurial technology have created a noninvasive mechanism to adjust medical stent positioning using magnetic reconfiguration.

From the William and Phyllis Mack Institute for Innovation Management

Four from Penn named 2025 Sloan Research Fellows
Four portraits arranged in a 2x2 grid. Clockwise from top left: Jason Altschuler, Cesar de la Fuente, Liang Wu, and Anderson Ye Zhang

Jason Altschuler (top left) and Anderson Ye Zhang (bottom left) of the Wharton School, Liang Wu (bottom right) of the School of Arts & Sciences, and César de la Fuente (top right) of the Perelman School of Medicine have been named 2025 Sloan Research Fellows. They are among 126 early-career scientists in North America chosen this year to receive the two-year, $75,000 fellowship in recognition of their accomplishments, creativity, and potential to become leaders in their fields.

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Four from Penn named 2025 Sloan Research Fellows

Jason Altschuler, César de la Fuente, Liang Wu, and Anderson Ye Zhang have been honored as early-career researchers and scholars for their accomplishments, creativity, and potential to become leaders in their fields.
Pursuing vaccines to stop celiac disease
A researcher holding a vaccine vial in a lab next to a microscope.

Image: iStock/nuttapong punna

Pursuing vaccines to stop celiac disease

Scientists at Penn’s Institute for RNA Innovation are using messenger RNA to stop the immune response that triggers celiac disease symptoms.

Alex Gardner

Is Moore’s Law really dead?
A semiconductor wafer.

According to Moore’s Law, the number of transistors on an integrated circuit will double every two years.

(Image: iStock/SweetBunFactory)

Is Moore’s Law really dead?

Penn Engineering’s Ben Lee and André DeHon discuss Moore’s Law, the observation that the number of transistors on an integrated circuit will double every two years with minimal rise in cost, and reflect on the consequences and opportunities of its possible end.

Devorah Fischler

Quantum communications
3D rendering of artist's interpretation of quantum entanglement.

Leveraging principles of quantum mechanics to securely transmit messages has promised a revolution in encryption, keeping sensitive information secure. Now, a collaborative team of researchers including the School of Engineering and Applied Science’s Liang Feng and Ph.D. candidate Yichi Zhang have developed a system that enables more stable, robust, high-efficiency, and long-range quantum communication—paving the way for practical, high-dimensional quantum networks.

(Image: Courtesy of Jian Fan)

Quantum communications

Penn and CUNY researchers collaborated to develop a device that uses quantum principles to relay information securely—an advance that could improve encryption in critical service areas like banking and health care.
Borrowing nature’s blueprint: How scientists replicated bone marrow
A chip with bioengineered bone marrow.

The new chip will allow for automated experiments, and can be connected to chip-based models of other organ systems, like the lungs.

(Image: Dan Huh)

Borrowing nature’s blueprint: How scientists replicated bone marrow

A collaborative research team from Penn Engineering, Penn Medicine, and the Children’s Hospital of Philadelphia have developed a chip that mimics human bone marrow.

Ian Scheffler

BEND lipids improve LNP mRNA delivery and gene editing
A gloved hand holding a beaker of lipids in a lab.

A sample of the new lipids, which improve the success rate of lipid nanoparticles delivering their contents.

(Image: Sylvia Zhang)

BEND lipids improve LNP mRNA delivery and gene editing

Penn Engineering researchers have developed a new class of lipids called branched endosomal disruptor (BEND) lipids to better deliver mRNA and gene-editing tools.

Ian Scheffler

Beth A. Winkelstein reappointed as deputy provost
Beth Winkelstein

Deputy Provost Beth A. Winkelstein.

(Image: Kevin Monko)

Beth A. Winkelstein reappointed as deputy provost

Winkelstein has taught at Penn for more than twenty years as a leader of interdisciplinary research, and has served as deputy provost since 2020.