Genetics | Penn Today

Penn and CHOP will test gene therapy for rare diseases with a new FDA trial protocol

A team led by Kiran Musunuru and Rebecca Ahrens-Nicklas of the Perelman School of Medicine and Children’s Hospital of Philadelphia will test the CRISPR framework for treating customized gene therapies for urea cycle disorders related to any one of seven genes.

Wild birds are driving the current U.S. bird flu outbreak

4 min. read

CRISPR gene-editing works to reduce high cholesterol in a new study

Kiran Musunuru of the Perelman School of Medicine comments on CRISPR gene-editing as a way to reduce cholesterol.

How a ‘one and done’ gene-editing treatment could lower cholesterol

Kiran Musunuru of the Perelman School of Medicine comments on a study that proved a single CRISPR gene-editing treatment at the highest dose could lower cholesterol.

Gene editing helped one baby—could it help thousands?

Kiran Musunuru and Rebecca Ahrens-Nicklas of the Perelman School of Medicine are attempting to shorten the length of a cutting-edge gene-editing therapy, previously produced in a record-breaking six months.

Kiran Musunuru: Editing genes to save lives

Kiran Musunuru develops gene-based therapies to improve the health of patients with heart disease and correct genetic changes in people affected by ultra-rare conditions.

Genetic testing isn’t common in adults. A new Penn study shows it should be

A study from the Perelman School of Medicine points to the advantages of universal genetic testing in intensive-care units. Theodore Drivas is quoted.

A doctor with a virtual pen hovering over a hologram of a kidney.

Penn-developed AI tools and datasets help tailor treatments for kidney patients

Penn Medicine and Wharton researchers have partnered to create CellSpectra and SISKA, offering clues to better treatments for kidney disease and beyond.

2 min. read

Genetic testing reduces risks from chemotherapy for gastrointestinal cancer patients

A new study by Penn Medicine’s Sony Tuteja finds that preemptive genetic testing for those with two specific genes cut chemotherapy side effects in half, as compared to similar patients given standard doses without testing.

What ever-growing incisors can teach us about genetic disease

An interdisciplinary team of researchers approaches the question ‘How do teeth mineralize?’ by analyzing the physical, biological, and genetic properties of teeth for real-world clinical applications in the future.