Correcting night blindness in dogs

Researchers in the School of Veterinary Medicine and colleagues have developed a gene therapy that restores dim-light vision in dogs with a congenital form of night blindness, offering hope for treating a similar condition in people.

Katherine Unger Baillie

In the News

Becker’s Hospital Review

Integrating genetic testing orders into EHRs saves time, study says

A study from the Perelman School of Medicine suggests that time is saved when clinicians are able to order genetic testing through electronic health record systems.



University of Pennsylvania receives $55 million gift to study, treat hereditary cancers

The $55 million gift from alumni Mindy and Jon Gray will be used to establish the Basser Cancer Interception Institute, featuring a statement from President Liz Magill.


Understanding metabolism genes might improve depression treatment

David Oslin of the Perelman School of Medicine discusses the implications of his latest research examining whether genetic testing can be used to help prescribe antidepressants.


Science Daily

Genomic differences selected through evolution may offer clues as to why COVID-19 outcomes vary widely

PIK Professor Sarah Tishkoff explains how her team’s studies use what happens in nature and signatures of natural selection to identify functionally important variants



Both nature and nurture contribute to signatures of socioeconomic status in the brain

Gideon Nave of the Wharton School and Martha Farah of the School of Arts & Sciences are quoted on their work that found evidence that both genetics and environmental influences contribute to the impact of socioeconomic status in a complex interplay with effects that span a variety of brain regions.



First gene-editing treatment injected into the blood reduces toxic protein for up to 1 year

Kiran Musunuru of the Perelman School of Medicine commented on an experimental gene-editing treatment for a condition that has already responded well to approved drugs. “I think people are generally assuming that the clinical outcomes [from the gene-editing treatment] will follow,” he said.