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Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer
Pancreatic cancer cells.

Image: Nemes Laszlo/Science Photo Library via Getty Images

Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer

Research led by Penn Vet’s Ellen Puré has used lipid nanoparticles to generate CAR T cells directed at a type of tumor support cells—cancer-associated fibroblasts—melting away the protective barrier around pancreatic tumor cells and paving the way for a potentially safer, more accessible, and cost-effective method to treat solid tumors.

3 min. read

A stiff defense: Rethinking gum disease
A section of healthy human gum tissue captured using an imaging technique called Second Harmonic Generation microscopy. In this sample, collagen fibers (shown in yellow), which give healthy gums their firm, resilient stiffness, are dense and well-organized—acting as a supportive scaffold for the surrounding cells (shown in teal).

A section of healthy human gum tissue captured using an imaging technique called Second Harmonic Generation microscopy. In this sample, collagen fibers (shown in yellow), which give healthy gums their firm, resilient stiffness, are dense and well-organized—acting as a supportive scaffold for the surrounding cells (shown in teal).

(Image: Hardik Makkar)

A stiff defense: Rethinking gum disease

Penn Dental Medicine’s Kyle H. Vining and Hardik Makkar take a biomaterials approach to understanding periodontal disease, using a hydrogel system to investigate how the physical properties of the gum tissue impact inflammation.
Analyzing the news with AI
A person standing inside multicoloured data sheets and social media chat icons organised into circular pattern.

Image: Andriy Onufriyenko via Getty Images

Analyzing the news with AI

Annenberg School for Communication postdoctoral fellow Baird Howland looks at prominent narratives in the news media and how they shape Americans’ worldviews.

Hailey Reissman

Who, What, Why: Kara Butler on museum education
Kara Butler talks at podium.

Kara Butler spoke at an event for Makuu: The Black Cultural Center about her experience growing up in Philadelphia.

nocred

Who, What, Why: Kara Butler on museum education

Butler, a fourth-year anthropology and communication double-major from Philadelphia, is starting a master’s program at the Graduate School of Education in the fall, with the goal of becoming a museum educator.
Music, friendship, and a podcast on the side
Emily Wilson, Kevin Platt, and Paul St. Amour seated with microphones at Kelly Writers House.

Emily Wilson, Kevin Platt, and Paul St. Amour recording an episode of SideGig at Kelly Writers House.

nocred

Music, friendship, and a podcast on the side

Through their new project, SideGig, School of Arts & Sciences faculty Paul Saint-Amour and Kevin Platt explore songs and sound. Plus, it gives the pals a chance to hang out.

From Omnia