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School of Veterinary Medicine

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Key to improving survival of transplanted retinal cells
Microscopic view of transplanted human cells.

Photomicrograph shows a small number of transplanted human cells (in red) that survived the stress of transplantation and were able to integrate and differentiate into cone photoreceptors in a partially degenerated canine retina.

(Image: Courtesy of Penn Vet)

Key to improving survival of transplanted retinal cells

Penn Vet researchers have identified metabolic stress as an obstacle to cell transplants, highlighting a critical window for cell-based retinal repair.

From Penn Vet

2 min. read

Penn Vet’s Thomas Parsons and Philadelphia-based tech firm AgriGates receive inaugural state innovation grants

Penn Vet’s Thomas Parsons and Philadelphia-based tech firm AgriGates receive inaugural state innovation grants

Thomas Parsons, Marie A. Moore Endowed Chair and director of Penn Vet’s Swine Teaching and Research Center, has pioneered a more efficient, humane way to feed mother pigs. Daniel Foy is the co-founder and CEO of the tech firm AgriGates, a Philadelphia firm that is turning technology into a next-generation tool for raising and managing livestock. The two are among the first recipients of Pennsylvania’s new Agricultural Innovation Grants, among 88 innovators from 45 counties that put forth cutting-edge solutions and technologies to move Pennsylvania agriculture into the future.

New Penn Vet study uncovers a key guardian of gut health and metabolism
Oriol Sunyer pointing to rainbow trout, the fish species used for the reported study.

Oriol Sunyer points out rainbow trout, the fish species used for the reported study.

(Image: Courtesy of Penn Vet)

New Penn Vet study uncovers a key guardian of gut health and metabolism

Researchers at the School of Veterinary Medicine unveil the critical role of secretory immunoglobulin M (sIgM) in maintaining microbiota balance, regulating metabolism, and protecting against disease.

Martin Hackett

2 min. read

Informing Pennsylvania public health and safety on deer ticks
A tiny deer tick in the palm of a hand.

Ticks are active when the temperature is above freezing, but their activity intensifies during the warmer months. Late-spring and summer are peak Lyme season, with the highest transmission occurring between May and August.

(Image: Olga Pankova)

Informing Pennsylvania public health and safety on deer ticks

A study of deer and ticks at the Penn’s School of Veterinary Medicine could shape public health and safety across the Commonwealth.

From Penn Vet

2 min. read

Keeping food safe and animals healthy
A lab technician injecting small eggs with a substance via syringe.

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Keeping food safe and animals healthy

As part of the Pennsylvania Animal Diagnostic Laboratory System (PADLS), Penn Vet’s New Bolton Center helps to protect animals and humans from health threats and minimize agricultural economic loss.

7 min. read

Improving T-cell responses to vaccines
Person in mask holding vaccine vial.

Image: franckreporter via Getty Images

Improving T-cell responses to vaccines

Penn Vet and Penn Medicine researchers have modified mRNA vaccines to include the cytokine IL-12 and improve T-cell responses which could improve the body’s ability to fight infections.

3 min. read

Determining the cause of cryopreservation fertility failures
Spermatogenesis at a microscopic level

Image: Ed Reschke via Getty Images

Determining the cause of cryopreservation fertility failures

A new study from Penn’s School of Veterinary Medicine on germ cell gene regulatory networks offers a holistic understanding of complex male germ cell differentiation in meiosis and spermatogenesis.

Martin Hackett

2 min. read

New tools to treat retinal degenerations at advanced stages of disease
Raghavi Sudharsan and William Beltran by a microscope in a lab.

Raghavi Sudharsan and William Beltran of the Division of Experimental Retinal Therapies at Penn’s School of Veterinary Medicine.

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New tools to treat retinal degenerations at advanced stages of disease

A collaborative team of researchers led by vision scientists at the School of Veterinary Medicine have developed novel promoters that drive strong and specific gene expression in rod and cone photoreceptors in mid-to-late stages of disease, potentially offering new and improved options for gene therapy.

3 min. read

Promising inhibitor combination for hard-to-treat leukemia subtypes
Andres Blanco in a lab at Penn Vet.

Andrés Blanco is an assistant professor of biomedical science at Penn’s School of Veterinary Medicine.

(Image: John Donges)

Promising inhibitor combination for hard-to-treat leukemia subtypes

Researchers from Penn Vet and other institutions have identified a novel inhibitor combination of molecules that induce terminal differentiation for the treatment of human non-APL subtypes of AML.

From Penn Vet

2 min. read