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mRNA Research
Pursuing vaccines to stop celiac disease
Pursuing vaccines to stop celiac disease
Scientists at Penn’s Institute for RNA Innovation are using messenger RNA to stop the immune response that triggers celiac disease symptoms.
Jonathan A. Epstein named head of Perelman School of Medicine and Penn Health System
Jonathan A. Epstein named head of Perelman School of Medicine and Penn Health System
Epstein has served as interim EVP and interim dean since December 2023.
How Penn is helping with bird flu research and disease surveillance
How Penn is helping with bird flu research and disease surveillance
Faculty are working on a vaccine for the H5N1 virus, studying its transmission, and helping the state test samples from birds and mammals.
Penn Center for Innovation celebrates 10 years
Penn Center for Innovation celebrates 10 years
The University’s nexus for technology transfer supports researchers in their innovative efforts, from CAR T to mRNA advancements that have dramatically reshaped the world.
Refining lipid nanoparticles for better mRNA therapies
Refining lipid nanoparticles for better mRNA therapies
A new method developed by Penn engineers for designing ionizable lipids is expected to have broad implications for mRNA-based vaccines and therapeutics.
Novel mRNA vaccine prevents and treat C. difficile
Novel mRNA vaccine prevents and treat C. difficile
Penn Medicine and the Children’s Hospital of Philadelphia have developed the first mRNA vaccine against C. difficile to successfully ward off the bacterial infection.
Siloxane-enhanced nanoparticles chart a new path in precision mRNA medicine
Siloxane-enhanced nanoparticles chart a new path in precision mRNA medicine
By adjusting the chemical structure of lipid nanoparticles Penn Engineers have discovered how to target specific organs, a major breakthrough in precision medicine.
A year after the Nobel Prize, Penn’s mRNA research is revving up
A year after the Nobel Prize, Penn’s mRNA research is revving up
In 2023, Drew Weissman and Katalin Karikó received Nobel Prize recognition for mRNA vaccines. Today, the work continues apace as successes across the University show how medicine is changing rapidly as a result of the prize-winning discovery.
Katalin Karikó, Nobel Laureate and pioneering mRNA researcher, named to Distinguished Daughters of Pennsylvania
Katalin Karikó, Nobel Laureate and pioneering mRNA researcher, named to Distinguished Daughters of Pennsylvania
Karikó was honored by Pennsylvania Governor Josh Shapiro at a special ceremony in Harrisburg.
Understanding the cellular mechanisms driving solid tumors’ robust defense system
Understanding the cellular mechanisms driving solid tumors’ robust defense system
Researchers from Penn have identified a “forcefield-like” defense system in solid tumors and the genetic elements that can switch it off.
In the News
The Hill
mRNA vaccine by UPenn scientists could manage bird flu outbreak
Researchers led by Scott Hensley of the Perelman School of Medicine have collaborated with Drew Weissman to develop an mRNA vaccine to treat the H5N1 avian flu.
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6ABC.com
Penn Medicine creates human bird flu vaccine
Researchers at Penn Medicine have created a human bird flu vaccine using mRNA, the same platform as the COVID-19 vaccine.
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Fast Company
Researchers are working on a new mRNA vaccine—this time for bird flu
Researchers led by Scott Hensley of the Perelman School of Medicine are developing an mRNA vaccine for the H5N1 avian flu with support from Nobel Prize cowinner Drew Weissman.
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Deutsche Welle
A vaccine for pancreatic cancer?
Drew Weissman of the Perelman School of Medicine comments on the efficacy of a potential pancreatic cancer vaccine.
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Scientific American
Pancreatic cancer vaccine shows promise in small initial trial
Drew Weissman of the Perelman School of Medicine is supportive of findings about a pancreatic cancer vaccine, though he says larger studies are needed to determine effectiveness.
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