Katalin Karikó, Nobel Laureate and pioneering mRNA researcher, named to Distinguished Daughters of Pennsylvania Katalin Karikó is a senior vice president at BioNTech and an adjunct professor of neurosurgery in the Perelman School of Medicine. (Image: Peggy Peterson/Courtesy of Penn Medicine) Katalin Karikó, Nobel Laureate and pioneering mRNA researcher, named to Distinguished Daughters of Pennsylvania Karikó was honored by Pennsylvania Governor Josh Shapiro at a special ceremony in Harrisburg.
Understanding the cellular mechanisms driving solid tumors’ robust defense system In a collaborative interdisciplinary study, Michael Mitchell of the School of Engineering and Applied Science, Wei Guo of the School of Arts & Sciences, and Drew Weissman of the Perelman School of Medicine show that solid tumors can block drug-delivery mechanisms with a “forcefield-like” effect but certain genetic elements that can effectively “shut down” the forcefield. Their findings hint at new targets for delivering cancer treatments that use the body’s immune system to fight tumors.(Image: iStock / CIPhotos) Understanding the cellular mechanisms driving solid tumors’ robust defense system Researchers from Penn have identified a “forcefield-like” defense system in solid tumors and the genetic elements that can switch it off.
Three from Penn elected to the American Philosophical Society From left: Dawn Bonnell, Katalin Karikó, and Drew Weissman.nocred Three from Penn elected to the American Philosophical Society Dawn Bonnell, Katalin Karikó, and Drew Weissman have been recognized for extraordinary achievements in their fields.
Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles Lipid nanoparticles present one of the most advanced drug delivery platforms to shuttle promising therapeutics such as mRNA but are limited by the time it takes to synthesize cationic lipids, a key component. Now, Michael Mitchell and his team at the School of Engineering and Applied Science have developed a faster way to make cationic lipids that are also more versatile, able to carry different kinds of treatments to target specific organs.(Image: iStock / Dr_Microbe) Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles New lipid platform enables rapid synthesis of molecules that can shuttle therapeutics for a range of diseases with a high degree of organ specificity.
mRNA vaccine by UPenn scientists could manage bird flu outbreak The Hill mRNA vaccine by UPenn scientists could manage bird flu outbreak Researchers led by Scott Hensley of the Perelman School of Medicine have collaborated with Drew Weissman to develop an mRNA vaccine to treat the H5N1 avian flu. Penn Medicine creates human bird flu vaccine 6ABC.com Penn Medicine creates human bird flu vaccine Researchers at Penn Medicine have created a human bird flu vaccine using mRNA, the same platform as the COVID-19 vaccine. Researchers are working on a new mRNA vaccine—this time for bird flu Fast Company Researchers are working on a new mRNA vaccine—this time for bird flu Researchers led by Scott Hensley of the Perelman School of Medicine are developing an mRNA vaccine for the H5N1 avian flu with support from Nobel Prize cowinner Drew Weissman. New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Like space shuttles using booster rockets to breach the atmosphere, lipid nanoparticles equipped with the new molecule more successfully deliver medicinal payloads. (Image: Courtesy of Penn Engineering) New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Penn Engineering researchers have invented a new way to synthesize the key chemical components of lipid nanoparticles that help protect and deliver medicinal payloads. Penn Vet launches mRNA Research Initiative Messenger RNA’s (mRNA) flexibility offers promising therapeutic and preventative solutions for a wide array of veterinary pathogens. Penn Vet is unlocking this potential by harnessing mRNA technology for the development of tailored veterinary vaccines. (Image: Adobe Stock) Penn Vet launches mRNA Research Initiative The University of Pennsylvania School of Veterinary Medicine today announced the mRNA Research Initiative to advance veterinary vaccine science. What makes a breakthrough? ‘Eight steps back’ before making it to the finish line (From left to right) Breakthrough Prize recipients Drew Weissman, Virginia M-Y Lee, Katalin Karikó, and Carl June at a reception on Feb. 13. (Image: Courtesy of Penn Medicine News) What makes a breakthrough? ‘Eight steps back’ before making it to the finish line Four of Penn’s Breakthrough Prize recipients, Carl June, Katalin Karikó, Virginia M-Y Lee, and Drew Weissman, were honored at a reception on Feb. 13. Load More
Penn Medicine creates human bird flu vaccine 6ABC.com Penn Medicine creates human bird flu vaccine Researchers at Penn Medicine have created a human bird flu vaccine using mRNA, the same platform as the COVID-19 vaccine. Researchers are working on a new mRNA vaccine—this time for bird flu Fast Company Researchers are working on a new mRNA vaccine—this time for bird flu Researchers led by Scott Hensley of the Perelman School of Medicine are developing an mRNA vaccine for the H5N1 avian flu with support from Nobel Prize cowinner Drew Weissman. New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Like space shuttles using booster rockets to breach the atmosphere, lipid nanoparticles equipped with the new molecule more successfully deliver medicinal payloads. (Image: Courtesy of Penn Engineering) New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Penn Engineering researchers have invented a new way to synthesize the key chemical components of lipid nanoparticles that help protect and deliver medicinal payloads. Penn Vet launches mRNA Research Initiative Messenger RNA’s (mRNA) flexibility offers promising therapeutic and preventative solutions for a wide array of veterinary pathogens. Penn Vet is unlocking this potential by harnessing mRNA technology for the development of tailored veterinary vaccines. (Image: Adobe Stock) Penn Vet launches mRNA Research Initiative The University of Pennsylvania School of Veterinary Medicine today announced the mRNA Research Initiative to advance veterinary vaccine science. What makes a breakthrough? ‘Eight steps back’ before making it to the finish line (From left to right) Breakthrough Prize recipients Drew Weissman, Virginia M-Y Lee, Katalin Karikó, and Carl June at a reception on Feb. 13. (Image: Courtesy of Penn Medicine News) What makes a breakthrough? ‘Eight steps back’ before making it to the finish line Four of Penn’s Breakthrough Prize recipients, Carl June, Katalin Karikó, Virginia M-Y Lee, and Drew Weissman, were honored at a reception on Feb. 13. Load More
Researchers are working on a new mRNA vaccine—this time for bird flu Fast Company Researchers are working on a new mRNA vaccine—this time for bird flu Researchers led by Scott Hensley of the Perelman School of Medicine are developing an mRNA vaccine for the H5N1 avian flu with support from Nobel Prize cowinner Drew Weissman. New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Like space shuttles using booster rockets to breach the atmosphere, lipid nanoparticles equipped with the new molecule more successfully deliver medicinal payloads. (Image: Courtesy of Penn Engineering) New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Penn Engineering researchers have invented a new way to synthesize the key chemical components of lipid nanoparticles that help protect and deliver medicinal payloads. Penn Vet launches mRNA Research Initiative Messenger RNA’s (mRNA) flexibility offers promising therapeutic and preventative solutions for a wide array of veterinary pathogens. Penn Vet is unlocking this potential by harnessing mRNA technology for the development of tailored veterinary vaccines. (Image: Adobe Stock) Penn Vet launches mRNA Research Initiative The University of Pennsylvania School of Veterinary Medicine today announced the mRNA Research Initiative to advance veterinary vaccine science. What makes a breakthrough? ‘Eight steps back’ before making it to the finish line (From left to right) Breakthrough Prize recipients Drew Weissman, Virginia M-Y Lee, Katalin Karikó, and Carl June at a reception on Feb. 13. (Image: Courtesy of Penn Medicine News) What makes a breakthrough? ‘Eight steps back’ before making it to the finish line Four of Penn’s Breakthrough Prize recipients, Carl June, Katalin Karikó, Virginia M-Y Lee, and Drew Weissman, were honored at a reception on Feb. 13.
New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Like space shuttles using booster rockets to breach the atmosphere, lipid nanoparticles equipped with the new molecule more successfully deliver medicinal payloads. (Image: Courtesy of Penn Engineering) New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control Penn Engineering researchers have invented a new way to synthesize the key chemical components of lipid nanoparticles that help protect and deliver medicinal payloads.
Penn Vet launches mRNA Research Initiative Messenger RNA’s (mRNA) flexibility offers promising therapeutic and preventative solutions for a wide array of veterinary pathogens. Penn Vet is unlocking this potential by harnessing mRNA technology for the development of tailored veterinary vaccines. (Image: Adobe Stock) Penn Vet launches mRNA Research Initiative The University of Pennsylvania School of Veterinary Medicine today announced the mRNA Research Initiative to advance veterinary vaccine science.
What makes a breakthrough? ‘Eight steps back’ before making it to the finish line (From left to right) Breakthrough Prize recipients Drew Weissman, Virginia M-Y Lee, Katalin Karikó, and Carl June at a reception on Feb. 13. (Image: Courtesy of Penn Medicine News) What makes a breakthrough? ‘Eight steps back’ before making it to the finish line Four of Penn’s Breakthrough Prize recipients, Carl June, Katalin Karikó, Virginia M-Y Lee, and Drew Weissman, were honored at a reception on Feb. 13.