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From WXPN host to WXPN ambassador: Kathy O’Connell announces retirement
Cathy O’Connell

After four decades, Cathy O’Connell and WXPN’s Kids Corner program are retiring.

(Image: Courtesy of WXPN)

From WXPN host to WXPN ambassador: Kathy O’Connell announces retirement

With O’Connell’s retirement, after four decades on air, the popular children’s program Kids Corner will end in June.

From WXPN

AI Month at Penn
People walking and seated near the entrance to Van Pelt Library.

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AI Month at Penn

A monthlong series of talks, workshops, symposia, and more highlights how recent advances in artificial intelligence are reshaping robotics, health, education, and public life, all the while keeping human values at the center.

2 min. read

Stress tested, testing stress: Novel organoid models how the adrenal gland develops
Michinori Mayama (left) is showing a culture dish to Kotaro Sasaki (right) in a lab.

Michinori Mayama (left) and Kotaro Sasaki (right). 

(Image: Courtesy of Kotaro Sasaki)

Stress tested, testing stress: Novel organoid models how the adrenal gland develops

Researchers led by Penn Vet’s Kotaro Sasaki and Michinori Mayama have developed an organoid system that faithfully mimics how the human adrenal gland develops and forms complex tissue structures, providing a powerful tool to study adrenal biology and laying the groundwork for regenerative therapies targeting adrenal diseases.
How a postwar research push changed Penn
Three men and one woman look at an item through a microscope in a HUP laboratory.

Researchers look through a microscope in a lab at the Hospital of the University of Pennsylvania around 1940.

(Image: Courtesy of University Archives)

How a postwar research push changed Penn

In the second of a limited series, “Chapters of Change” showcases another transformational moment in Penn’s past shaped by changes in society—World War II—during which the U.S.’s drive for knowledge sparked massive investments in research.
Mikhaidia Miller: First-gen perspectives on nursing, health equity, and what’s next
Mikhaidia Miller wearing a striped sweater and standing with arms crossed, smiling and facing sideways, in the Penn First Plus office.

A first-generation student graduating from the School of Nursing, fourth-year Mikhaidia Miller has benefited from Penn First Plus mentorship, programming, and resources throughout her time at Penn. She aims to become a certified registered nurse anesthetist and help improve health equity for all patients.

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Mikhaidia Miller: First-gen perspectives on nursing, health equity, and what’s next

The fourth-year reflects on what underpins her desire to pursue a nursing career and how Penn First Plus has supported her as a first-generation student.

3 min. read

Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer
Pancreatic cancer cells.

Image: Nemes Laszlo/Science Photo Library via Getty Images

Targeting tumor supporting cells: Advancing CAR T success in pancreatic cancer

Research led by Penn Vet’s Ellen Puré has used lipid nanoparticles to generate CAR T cells directed at a type of tumor support cells—cancer-associated fibroblasts—melting away the protective barrier around pancreatic tumor cells and paving the way for a potentially safer, more accessible, and cost-effective method to treat solid tumors.
How does medicine come to be?
A bowl of dried ginger root for traditional Chinese medicine.

Image: LightStock via Getty Images

How does medicine come to be?

By tracing substances from their roots to how they’re used today, a team including Hsiao-Wen Cheng of the Department of East Asian Languages and Civilizations aims to answer questions about how medical practices evolve.

From Omnia

The big reveal: Penn Medicine’s Match Day 2026
Two Penn Med students and two others under a 2026 balloon at Penn’s 2026 Match Day.

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The big reveal: Penn Medicine’s Match Day 2026

The Perelman School of Medicine’s graduating class of 2026 celebrated Match Day on March 20, revealing the location of their residencies with a celebration among faculty, friends, and family.

1 min. read

A stiff defense: Rethinking gum disease
A section of healthy human gum tissue captured using an imaging technique called Second Harmonic Generation microscopy. In this sample, collagen fibers (shown in yellow), which give healthy gums their firm, resilient stiffness, are dense and well-organized—acting as a supportive scaffold for the surrounding cells (shown in teal).

A section of healthy human gum tissue captured using an imaging technique called Second Harmonic Generation microscopy. In this sample, collagen fibers (shown in yellow), which give healthy gums their firm, resilient stiffness, are dense and well-organized—acting as a supportive scaffold for the surrounding cells (shown in teal).

(Image: Hardik Makkar)

A stiff defense: Rethinking gum disease

Penn Dental Medicine’s Kyle H. Vining and Hardik Makkar take a biomaterials approach to understanding periodontal disease, using a hydrogel system to investigate how the physical properties of the gum tissue impact inflammation.

3 min. read