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Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy
Hand holding a microdevice

Penn engineers and collaborators have developed a transparent, micro-engineered device that houses a living, vascularized model of human lung cancer—a “tumor on a chip”—and show that the diabetes drug vildagliptin helps more CAR T cells break through the tumor’s defenses and attack it effectively.

(Image: Courtesy of Dan Huh)

Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy

Penn engineers and collaborators have built a living tumor on a chip to expose how cancers block immune attacks, and how one existing drug could make immunotherapy like CAR T more effective against solid tumors.

3 min. read

Two Penn faculty elected American Physical Society Fellows
Ritesh Agarwal and Doug Jerolmack.

Ritesh Agarwal (left), Srinivasa Ramanujan Distinguished Scholar in Materials Science and Engineering, and Douglas Jerolmack, Edmund J. and Louise W. Kahn Endowed Term Professor of Earth and Environmental Science and professor of mechanical engineering and applied mechanics.

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Two Penn faculty elected American Physical Society Fellows

Ritesh Agarwal of the School of Engineering and Applied Science and Douglas Jerolmack of the School of Arts & Sciences and Penn Engineering have been elected by their peers in recognition of their contributions to the field.

2 min. read

Eva Dyer is listening to the brain’s code with a little help from AI
Eva Dyer

Eva Dyer is the Rachleff Associate Professor in Bioengineering and in computer and information science at the School of Engineering and Applied Science.

(Image: Courtesy of Penn Engineering)

Eva Dyer is listening to the brain’s code with a little help from AI

Penn professor Eva Dyer merges her background in music and audio engineering with artificial intelligence to help uncover brain signals and explore how the brain processes information.

Melissa Pappas

2 min. read

AI at the eyelid: Glasses that track health through your blinks
Dongyin Hu models BlinkWise glasses at his computer station.

Penn Engineering graduate student Dongyin Hu models BlinkWise, an AI-powered system that uses radio waves to monitor blinks and eye health.

(Image: Sylvia Zhang)

AI at the eyelid: Glasses that track health through your blinks

Researchers at Penn Engineering have developed BlinkWise, an AI-powered system that uses radio waves to monitor blinks and eye health.

Ian Scheffler

2 min. read

Uncovering new antibiotics with AI 

Uncovering new antibiotics with AI 

César de la Fuente leverages machine learning to accelerate the discovery of lifesaving drugs and help reduce antibiotic resistance, a rising global health problem.

Helping robots work together to explore the Moon and Mars
forthcoming

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Helping robots work together to explore the Moon and Mars

Penn Engineers, NASA, and five other universities tested robotic systems designed to help unmanned explorers cooperate in the dunes of White Sands, New Mexico, paving the way for Moon and Mars exploration.

5 min. read

Students test one way to combat extreme heat in Philadelphia
Nafisa Bangura (left) and Angelica Dadda (right) doing hands-on experimental work in the Composto Lab.

Nafisa Bangura (left) and Angelica Dadda (right) examine CoolSeal-treated asphalt bricks in the Composto Lab to better understand how this coating behaves in controlled environments.

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Students test one way to combat extreme heat in Philadelphia

Third-year students Nafisa Bangura and Angelica Dadda expanded upon a multidisciplinary research endeavor to evaluate a reflective pavement coating as a tool to mitigate extreme heat. Their work may inform policy efforts to improve urban heat resilience.

4 min. read

A generative AI model that designs new antibiotics
Pranam Chatterjee in his lab at Penn Engineering.

The lab of Pranam Chatterjee (pictured), in collaboration with the lab of César de la Fuente, developed and validated a new “diffusion model” that can generate antibiotic candidates the same way AI creates images.

(Image: Sylvia Zhang)

A generative AI model that designs new antibiotics

A research team at Penn Engineering has developed and validated a new ‘diffusion model’ that can generate antibiotic candidates the same way AI creates images.

Ian Scheffler

2 min. read

Penn Engineers send quantum signals with standard internet protocol
Yichi Zhang wearing sunglasses in the Penn Engineering lab.

Yichi Zhang, a doctoral student in materials science and engineering, inspects the source of the quantum signal.

(Image: Sylvia Zhang)

Penn Engineers send quantum signals with standard internet protocol

Penn engineers have developed a “Q-Chip” (quantum-classical hybrid internet by photonics) signal which coordinates quantum and classical data and can run on the same infrastructure that carries everyday online traffic.

Ian Scheffler

2 min. read

A new way to guide light
Researchers stand and point at a white board littered with equations.

Bo Zhen (right) and postdoctoral researcher Li He developed a system for guiding light through tiny crystals in ways that allow it to navigate undeterred bu bumps and defects. Their work could lead to sturdier lasers, faster data links, and light-based chips that don’t get tripped up by imperfections.

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A new way to guide light

Penn researchers developed a system that allows light to be guided through a tiny crystal, undeterred by bumps, bends, and back-reflections. Their findings pave the way for robust, controllable light-based chips, smarter routing for data links, and more stable lasers.

3 min. read