Perelman School of Medicine

A new method to increase effectiveness of nanomedicines

Penn Medicine researchers have developed a new technique that uses complement inhibitor Factor I to prevent proteins from attacking treatment-carrying nanoparticles so they can better reach targets within the body.

Sophie Kluthe



In the News


Vox.com

Am I asymptomatic, or do I just really not want to have Covid-19? A guide

Michael David of the Perelman School of Medicine explained why there are few concrete guidelines regarding asymptomatic COVID-19 infections. “Currently, there are no data available to define ‘asymptomatic,’ which can be different in different people, given that many have chronic respiratory symptoms as baseline, from congestive heart failure to allergies,” he said.

FULL STORY →



Boston Globe

‘This is a different phase.’ It may be time for a reset on kids, school, and COVID

David Rubin of the Perelman School of Medicine co-developed new proposed guidelines for managing COVID-19 in schools, which include ending testing for asymptomatic children. “The issues around prolonging social isolation or continuing to deny access to in-person education are so far greater than the risk of the virus itself. Not just to the children but to their families themselves, particularly now that people can get vaccinated,” he said.

FULL STORY →



Reuters

Fact Check-Why those with comorbidities are still counted as COVID-19 deaths

Susan Ellenberg of the Perelman School of Medicine said understanding comorbidities can reveal different populations’ risk of disease. “A comorbidity may contribute to the severity of the disease under consideration ... but the underlying cause of death would not be the comorbidity,” she said.

FULL STORY →



Bloomberg

Biogen Alzheimer’s drug coverage threatens minorities’ access

Holly Fernandez Lynch of the Perelman School of Medicine spoke about the obstacles preventing less-privileged people from participating in clinical trials. “You typically have to live near the trial site or have the resources to travel. You have to be able to take time away from work and your caregivers need to do the same. You have to have reliable transportation,” she said.

FULL STORY →



The Washington Post

The ethics of a second chance: Pig heart transplant recipient stabbed a man seven times years ago

Scott Halpern of the Perelman School of Medicine spoke about the importance of maintaining separation between legal and medical systems. “We have a legal system designed to determine just redress for crimes,” he said. “And we have a health-care system that aims to provide care without regard to people’s personal character or history.”

FULL STORY →