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Collaborating toward a better future for all
Group pose of Draw Down the Lightning grants winners.

Winners of the inaugural Draw Down the Lightning grants with Penn President J. Larry Jameson and Senior Vice President for Strategic Initiatives David Asch.

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Collaborating toward a better future for all

The 12 winning teams of the inaugural Draw Down the Lightning grants were celebrated by Penn leadership at a reception, bringing to life the vision of In Principle and Practice.

4 min. read

Armoring CAR T cells to take on cancer
3D visualization showing a reddish-blue tumor mass with internal vasculature, surrounded by blue CAR T cells and small extracellular vesicles against a dark background.

Wei Guo of the School of Arts & Sciences and colleagues from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science have teamed up to uncover how solid tumors’ complicated microenvironments can manipulate cancer-fighting CAR T cells through extracellular vesicles, causing the engineered CAR T cells to commit fratricide—essentially turning against each other instead of attacking the cancer.

(Image: iStock / Marcin Klapczynski)

Armoring CAR T cells to take on cancer

Wei Guo of the School of Arts & Sciences and colleagues from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science have uncovered how solid tumors manipulate cancer-fighting CAR T cells through extracellular vesicles, causing the engineered CAR T cells to commit fratricide—essentially turning against each other instead of attacking the cancer.

3 min. read

Five Penn faculty elected to the American Academy of Arts and Sciences
Top row: Dennis Discher, Michael Correa-Jones, and Cherie Kagan. Bottom row: Sophie Rosenfeld and Susan Weiss.

Top row: Dennis Discher, Michael Correa-Jones, and Cherie Kagan. Bottom row: Sophie Rosenfeld and Susan Weiss.

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Five Penn faculty elected to the American Academy of Arts and Sciences

Dennis E. Discher, Michael Jones-Correa, Cherie R. Kagan, Sophia Rosenfeld, and Susan R. Weiss are being recognized for their contributions to engineering, political science, history, and biology.

3 min. read

COVID vaccine protected kids from long COVID

COVID vaccine protected kids from long COVID

New research from Penn Medicine biostatistics professor Yong Chen finds that vaccines kept children and adolescents from developing long COVID by blocking COVID-19 infections from the start, instead of special protection against the virus.

Wyss donation creates Penn orthoplastic surgery hub

Wyss donation creates Penn orthoplastic surgery hub

The $4.9 million donation from the Wyss Medical Foundation will create the Wyss Orthoplastic Global Education and Innovation Hub at Penn Medicine. The Hub will conduct research, create fellowships, and establish a conference in the emerging field of orthoplastic surgery, which combines expertise from both plastic and orthopaedic surgery.

Shelley Berger honored by AACR for cancer research

Shelley Berger honored by AACR for cancer research

Berger, the Daniel S. Och University Professor with appointments in the Perelman School of Medicine department of Cell & Developmental Biology and a Penn Integrates Knowledge Professor in the School of Arts & Sciences, is recognized for her outstanding contributions to cancer research by the American Association for Cancer Research with the 2025 AACR-Women in Cancer Research Charlotte Friend Lectureship.

Match Day sees future MDs planning medical careers back home, and at Penn
A Penn Med student putting a pin in a map on Match Day 2025.

Image: Courtesy of Penn Medicine News

Match Day sees future MDs planning medical careers back home, and at Penn

Graduating students at Penn’s Perelman School of Medicine gathered with friends and family for the annual Match Day celebration in the Atrium in the Jordan Medical Education Center; at noon, their opened envelopes revealed their next steps for residency.

Meredith Mann

Laughing gas: An old drug’s new trick to fight depression
A laughing gas mask hovering over a patient’s perspective.

Image: vzmaze via Getty Images

Laughing gas: An old drug’s new trick to fight depression

Researchers at the Perelman School of Medicine have uncovered how nitrous oxide, an anesthetic used worldwide since the 19th century, could help lift mood fast in people with depression that resists other treatments.

From Penn Medicine News

1 min. read

Scientists unlock frogs’ antibacterial secrets to combat superbugs
A tree frog in Thailand.

The researchers theorized that frogs must have developed antibiotics to survive in their challenging environment.

Image: Michael Edward via Getty Images

Scientists unlock frogs’ antibacterial secrets to combat superbugs

The lab of César de la Fuente has created synthetic peptides, a class of antibiotics, derived from the secretions of a frog commonly found in South Asia.

Ian Scheffler

2 min. read