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Mapping the links between brain development and mental health
Sheet of a child’s brain scans.

A collaborative team led by Theodore D. Satterthwaite, Golia Shafiei, and Michael P. Milham has developed a large-scale, open data resource for mapping brain development and its associations with mental health.

(Image: fmajor via Getty Images)

Mapping the links between brain development and mental health

A new large-scale, open data resource from the Perelman School of Medicine and collaborators helps researchers link brain development with mental health disorders.

3 min. read

Penn nurse manager brings health resources to her tribal community
Sherry Caputo in front of the Lenape Tribal Grounds building.

Image: Courtesy of Sherry Caputo

Penn nurse manager brings health resources to her tribal community

Outside of her day job as a nurse manager for Penn Medicine at Home, Sherry “Strong Sun Spirit” Caputo has helped bring mental health education, COVID resources, and nutrition programming to her tribal community, the Nanticoke Lenni-Lenape Tribal Nation in New Jersey.

2 min. read

After a pulmonary embolism, a runner’s rapid save
Molly Fadden.

Penn Medicine is one of the health systems that has been trialing a new catheter device for embolectomies since 2024. Molly Fadden (pictured) agreed to the use of the trial device in her procedure.  

(Image: Courtesy of Penn Medicine Magazine)

After a pulmonary embolism, a runner’s rapid save

A pulmonary embolism is life-threatening—and urgent. For Molly Fadden, Penn Medicine was ready to get her to the right experts, right in time.

Christina Hernandez Sherwood for Penn Medicine Magazine

2 min. read

Clock changes disrupt sleep, health, and well-being
A person turning back a clock superimposed over a profile of a head and day and night icons.

Image: Rudzhan Nagiev via Getty Images

Clock changes disrupt sleep, health, and well-being

Indira Gurubhagavatula of the Perelman School of Medicine explains how seasonal time changes affect the body’s internal clock, and offers tips for an easier transition.

3 min. read

A PATH to hospital at home
Julia Borgesi working at a standing computer desk.

For some patients, there are advantages that go beyond the comfort and convenience of staying at home. When seeing a patient in their home setting, a member of the PATH team like Julia Borgesi (pictured) can identify potential issues that may be contributing to poor health outcomes.

(Image: Courtesy of Penn Medicine News)

A PATH to hospital at home

An innovative Penn Medicine program shows the impact of offering certain patients acute care in the comfort of their homes instead of being admitted to the hospital.

From Penn Medicine News

2 min. read

Penn Cardiovascular Institute director honored as Distinguished Scientist

Penn Cardiovascular Institute director honored as Distinguished Scientist

Daniel P. Kelly, the Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases and director of the Penn and Children’s Hospital of Philadelphia Cardiovascular Institutes, has been named a 2025 Distinguished Scientist by the American Heart Association for contributions to cardiovascular, stroke, and brain health research.

After the hospital, support to help patients thrive at home
Mike Desalis seated at home next to his walker.

Image: Courtesy of Penn Medicine News

After the hospital, support to help patients thrive at home

A Penn program offers low-income patients extra support after a hospital stay—with virtual teams knitting together a safety net to reduce readmissions.

From Penn Medicine News

2 min. read

Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy
Hand holding a microdevice

Penn engineers and collaborators have developed a transparent, micro-engineered device that houses a living, vascularized model of human lung cancer—a “tumor on a chip”—and show that the diabetes drug vildagliptin helps more CAR T cells break through the tumor’s defenses and attack it effectively.

(Image: Courtesy of Dan Huh)

Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy

Penn engineers and collaborators have built a living tumor on a chip to expose how cancers block immune attacks, and how one existing drug could make immunotherapy like CAR T more effective against solid tumors.

3 min. read

$27.2M national effort launches to unify Alzheimer’s research data

$27.2M national effort launches to unify Alzheimer’s research data

Yong Chen, Leonard Davis Institute senior fellow and professor of biostatistics, epidemiology, and informatics at the Perelman School of Medicine, has been selected by the National Institute on Aging initiative to establish a collaborative network and data ecosystem to accelerate discovery and improve prevention, detection, and treatment strategies for Alzheimer’s disease and related dementias.

Penn Medicine, CHOP researchers elected to National Academy of Medicine

Penn Medicine, CHOP researchers elected to National Academy of Medicine

The newly-elected members are Gerd A. Blobel, co-director of Penn's Epigenetics Institute; Enrique Schisterman, chair and Perelman Professor of biostatistics, epidemiology, and informatics; and Katalin Susztak, professor of nephrology and genetics and director of the Kidney Innovation Center at Penn and CHOP.