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New mRNA therapy could repair damaged lungs
Rendering of damaged lungs.

Image: iStock/Design Cells

New mRNA therapy could repair damaged lungs

Penn researchers have designed an organ-specific mRNA and lipid nanoparticle therapy which could lead to new targeted treatments for damaged organs.

Alex Gardner

Getting to the root of root canals
Person receiving treatment in a dental clinic.

Image: Courtesy of Penn Dental Medicine/Peter Olson Photography

Getting to the root of root canals

Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.
With hemophilia B, a lifetime of worry eased with one infusion
An infusion bag hanging in a hospital room.

Image: iStock/Isaac Lee

With hemophilia B, a lifetime of worry eased with one infusion

The first Penn Medicine patient to receive an FDA-approved new gene therapy for hemophilia B can now stop regular prophylactic clotting factor injections.

From Penn Medicine News

Four from Penn named 2025 Sloan Research Fellows
Four portraits arranged in a 2x2 grid. Clockwise from top left: Jason Altschuler, Cesar de la Fuente, Liang Wu, and Anderson Ye Zhang

Jason Altschuler (top left) and Anderson Ye Zhang (bottom left) of the Wharton School, Liang Wu (bottom right) of the School of Arts & Sciences, and César de la Fuente (top right) of the Perelman School of Medicine have been named 2025 Sloan Research Fellows. They are among 126 early-career scientists in North America chosen this year to receive the two-year, $75,000 fellowship in recognition of their accomplishments, creativity, and potential to become leaders in their fields.

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Four from Penn named 2025 Sloan Research Fellows

Jason Altschuler, César de la Fuente, Liang Wu, and Anderson Ye Zhang have been honored as early-career researchers and scholars for their accomplishments, creativity, and potential to become leaders in their fields.
Pursuing vaccines to stop celiac disease
A researcher holding a vaccine vial in a lab next to a microscope.

Image: iStock/nuttapong punna

Pursuing vaccines to stop celiac disease

Scientists at Penn’s Institute for RNA Innovation are using messenger RNA to stop the immune response that triggers celiac disease symptoms.

Alex Gardner

Researchers create genetic map tied to kidney disease
microscopic rendering of DNA strands.

Image: iStock/TanyaJoy

Researchers create genetic map tied to kidney disease

The creation of the most complete map of more than 1,000 genes that influence kidney function could help experts diagnose and design targeted treatments for kidney disease.

Alex Gardner

Rate of suicide higher in individuals with headaches
A person holding their head in pain near a window.

Image: iStock/Ake Ngiamsanguan

Rate of suicide higher in individuals with headaches

New research from Penn Medicine finds that suicide attempt and completion is highest among individuals with headaches from head injuries, but also elevated in individuals with mild headaches.

Kelsey Geesler

Catherine and Anthony Clifton make transformational gift to accelerate patient care, research, and education at Penn Medicine
Seven people including Penn President J. Larry Jameson, Catherine and Anthony Clifton, Kevin Mahoney, and Jon Epstein.

From left to right, Penn Medicine Board Chair Dhan Pai; Interim Penn President J. Larry Jameson; donors Catherine and Anthony Clifton; Hospital of the University of Pennsylvania CEO Regina Cunningham; University of Pennsylvania Health System CEO Kevin B. Mahoney; and Interim EVP of the University for the Health System and Perelman School of Medicine Dean Jonathan A. Epstein.

(Image: Eddy Marenco)

Catherine and Anthony Clifton make transformational gift to accelerate patient care, research, and education at Penn Medicine

The Pavilion will be renamed in recognition of the Cliftons’ historic philanthropic commitment, one of the largest ever to name a U.S. inpatient hospital building.