Raghavi Sudharsan and William Beltran of the Division of Experimental Retinal Therapies at Penn’s School of Veterinary Medicine.
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New tools to treat retinal degenerations at advanced stages of disease
A collaborative team of researchers led by vision scientists at the School of Veterinary Medicine have developed novel promoters that drive strong and specific gene expression in rod and cone photoreceptors in mid-to-late stages of disease, potentially offering new and improved options for gene therapy.
Soon-to-be-graduate hopes to deliver primary care to rural communities
Fueled by his faith, Chip Chambers, a fifth-year M.D./M.B.A. student in the Perelman School of Medicine and Wharton School, has always looked for ways to serve.“My faith is a huge motivator of everything that I do. I just believe that I’ve been blessed with a lot of things that I didn’t earn and that I have a responsibility to steward those for the good of other people and not for myself,” Chambers says.
Kendra Domotor may have “zigzagged” her way to dentistry, but her journey helped her find her center in dentistry, helping her blend her love of science, teaching, and service.
Image: Kevin Monko; Courtesy of Penn Dental Medicine.
Commonly prescribed medications for high blood pressure have unexpected side effects
Henry Daniell of Penn Dental and collaborators found that ACE inhibitors dramatically reduced the activity of ACE2, a critical cardioprotective enzyme.
“Our results showed that simple, low-cost nudges can help teachers support student progress in math,” says Penn psychology professor Angela Duckworth.
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A simple way to boost math progress
Researchers from Penn’s Behavior Change for Good Initiative and their collaborators conducted a megastudy to investigate whether low-cost nudges–informed by behavioral science–could help teachers accelerate student progress in math.
Gustavo D. Aguirre and Leonardo Murgiano of the School of Veterinary Medicine of the University of Pennsylvania.
(Image: John Donges)
New genetic cause of blindness in dogs
In collaboration with a foundation that breeds service dogs for the visually impaired, researchers at the School of Veterinary Medicine at the University of Pennsylvania and the University of Padova in Padova, Italy, have identified a novel variant associated with progressive retinal atrophy in three Labrador retrievers.
An antiviral chewing gum to reduce influenza and herpes simplex virus transmission
Researchers at Penn Dental Medicine and collaborators have used a clinical-grade antiviral chewing gum to substantially reduce viral loads of two herpes simplex viruses and two influenza A strains in experimental models.
Innate immune training aggravates inflammatory bone loss
Researchers from the School of Dental Medicine and international collaborators from Germany have investigated the effects of training the innate immune system in experimental models of chronic inflammatory disease, periodontitis and arthritis.
Image: Courtesy of Penn Dental Medicine/Peter Olson Photography
Getting to the root of root canals
Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.
