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Gene therapy may slow loss of motor function in ALS
A microscopic rendering of a neuromuscular junction.

Image: Koto_Feja via Getty Images

Gene therapy may slow loss of motor function in ALS

Researchers at the Perelman School of Medicine and Children's Hospital of Philadelphia used RNA interference to silence a key protein that causes ALS, showing promise for treating the devastating neurodegenerative disease.

Kelsey Geesler

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That’
Cover of Elusive Cures book next to headshot of Nicole Rust.

Tackling brain conditions, says psychology professor Nicole Rust, requires thinking about the brain not as a domino chain but as a complex dynamical system with feedback loops.

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  • Q&A

    • ‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That’

    The first book from psychology professor Nicole Rust of the School of Arts & Sciences dives into why research on conditions like Alzheimer’s and depression hasn’t translated more effectively into better treatments.

    5 min. read

    Neurobowl reimagines how the next generation of neurologists is trained
    Sashank Prasad and Raymond Price.

    Sashank Prasad (left), chief of Neurology at Penn Presbyterian Medical Center, and Raymond Price, chief of Neurology at Pennsylvania Hospital.

    (Image: Courtesy of Penn Medicine News)

    Neurobowl reimagines how the next generation of neurologists is trained

    Sashank Prasad and Raymond Price have collaborated for years on an online quiz-show to teach uncommon neurological conditions for Penn Medicine students, and have introduced the program to other institutions as well.

    From Penn Medicine News

    2 min. read

    What behavioral strategies motivate environmental action?
    Drawing of people in park.

    Image: Irina_Strelnikova via Getty Images

    What behavioral strategies motivate environmental action?

    A collaborative study from researchers affiliated with the Annenberg School for Communication, Annenberg Public Policy Center, and School of Arts & Sciences tested 17 strategies in an “intervention tournament.”

    4 min. read

    National Academy of Sciences elects four from Penn
    Four headshots of Penn Faculty. Top left tile clockwise: Mark Devlin, Katalin Karikó, E. John Wherry III, and Virginia M.Y. Lee

    Four faculty have been elected to the National Academy of Sciences in recognition of their innovative contributions to original scientific research. The newly honored scholars are Mark Devlin (top left) from the School of Arts & Sciences and Katalin Karikó (top right), Virginia M.Y. Lee (bottom left), and E. John Wherry III (bottom right) from the Perelman School of Medicine.

    nocred

    National Academy of Sciences elects four from Penn

    The newly elected members, recognized for their innovative contributions to original research, are Mark Devlin of the School of Arts & Sciences and Katalin Karikó, Virginia Lee, and E. John Wherry III of the Perelman School of Medicine.

    3 min. read

    Laughing gas: An old drug’s new trick to fight depression
    A laughing gas mask hovering over a patient’s perspective.

    Image: vzmaze via Getty Images

    Laughing gas: An old drug’s new trick to fight depression

    Researchers at the Perelman School of Medicine have uncovered how nitrous oxide, an anesthetic used worldwide since the 19th century, could help lift mood fast in people with depression that resists other treatments.

    From Penn Medicine News

    1 min. read