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Veterinary Medicine

A new Penn Vet clinic brings support and hope for dogs with retinal disease
A dog having a retinal scan at Penn Vet.

Image: Courtesy of Penn Vet

A new Penn Vet clinic brings support and hope for dogs with retinal disease

When Zoey the cockapoo developed a fear of the dark, her owner, Adam Weitz, sought a veterinary ophthalmologist. The grim news was that Zoey had progressive retinal atrophy (PRA), a category of genetic, blindness-causing diseases that have no cure. Zoey would be totally blind in two years, he was told.

From Penn Vet

2 min. read

White coat ceremonies: A professional milestone
Four students celebrating in white coats after Penn’s white coat ceremony.

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White coat ceremonies: A professional milestone

The School of Dental Medicine, Perelman School of Medicine, and School of Veterinary Medicine marked the start of the semester with white coat ceremonies for their students.

2 min. read

Penn Vet’s next gen biomedical scientists present their research at the annual Veterinary Scholars Symposium

Penn Vet’s next gen biomedical scientists present their research at the annual Veterinary Scholars Symposium

Two dozen Penn Vet students unveiled the original research they conducted as funded participants in the National Institutes of Health(NIH)/Boehringer Ingelheim Summer Research Program at the annual Veterinary Scholars Symposium in Spokane, Washington in August.

A Penn Vet care team collaborates to treat a dog with a strong will but a sick heart
Elizabeth Mauldin with her dog Little Dove outside of Penn Vet.

Elizabeth Mauldin, a dermapathologist at Penn Vet, has owned Little Dove since she was a pup.

(Image: Courtesy of Penn Vet News)

A Penn Vet care team collaborates to treat a dog with a strong will but a sick heart

A team of experts at Penn’s School of Veterinary Medicine stabilized and diagnosed a tricky disease through teamwork and quick action.

From Penn Vet

2 min. read

Foraging patterns and preferences of local honeybees
A person in a beekeeper suit holding a panel covered in bees and honeycomb.

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Foraging patterns and preferences of local honeybees

A new Penn Vet study aims to shed light on honeybees’ foraging habits, with an eye toward aiding their survival.

From Penn Vet

4 min. read

Mitochondrial vulnerability and neurovasculature function connection impacts neuropsychiatric disease

Mitochondrial vulnerability and neurovasculature function connection impacts neuropsychiatric disease

In a new study led by Penn’s School of Veterinary Medicine and Children’s Hospital of Philadelphia, researchers have found that mitochondrial dysfunction in the blood-brain barrier may lead to neuropsychiatric disease in some patients with 22qDS. The researchers also demonstrate that a class of FDA-approved cholesterol drugs could potentially be repurposed to treat this dysfunction.

Researchers advance mRNA delivery to the retina using stabilized lipid carriers

Researchers advance mRNA delivery to the retina using stabilized lipid carriers

The efficient delivery of synthetic mRNA to the retina has been a barrier to mRNA-based treatments for vision loss. A new study from Penn Vet has found that coating mRNA-lipid complexes (lipoplexes) with polyethylene glycol (PEG)-lipid derivatives can enhance their stability and penetration into retinal tissue.

Key to improving survival of transplanted retinal cells
Microscopic view of transplanted human cells.

Photomicrograph shows a small number of transplanted human cells (in red) that survived the stress of transplantation and were able to integrate and differentiate into cone photoreceptors in a partially degenerated canine retina.

(Image: Courtesy of Penn Vet)

Key to improving survival of transplanted retinal cells

Penn Vet researchers have identified metabolic stress as an obstacle to cell transplants, highlighting a critical window for cell-based retinal repair.

From Penn Vet

2 min. read

New device could streamline vision-saving therapies

New device could streamline vision-saving therapies

A new study by a team of vision scientists from the Division of Experimental Retinal Therapies at Penn Vet, led by William A. Beltran, have worked to demonstrate that a novel surgical tool used previously in gene and cell therapy clinical trials can place therapies directly beneath the retina using a minimally invasive approach.

Penn Vet’s Thomas Parsons and Philadelphia-based tech firm AgriGates receive inaugural state innovation grants

Penn Vet’s Thomas Parsons and Philadelphia-based tech firm AgriGates receive inaugural state innovation grants

Thomas Parsons, Marie A. Moore Endowed Chair and director of Penn Vet’s Swine Teaching and Research Center, has pioneered a more efficient, humane way to feed mother pigs. Daniel Foy is the co-founder and CEO of the tech firm AgriGates, a Philadelphia firm that is turning technology into a next-generation tool for raising and managing livestock. The two are among the first recipients of Pennsylvania’s new Agricultural Innovation Grants, among 88 innovators from 45 counties that put forth cutting-edge solutions and technologies to move Pennsylvania agriculture into the future.