5/18
Health Sciences
One Protein, Two Personalities: Penn Team Identifies New Mechanism of Cancer Spread
Cancer involves a breakdown of normal cell behavior. Cell reproduction and movement go haywire, causing tumors to grow and spread through the body.
Penn Medicine: Dietary Amino Acids Relieve Sleep Problems after Traumatic Brain Injury in Animals
A new study suggests a potential dietary treatment - a cocktail of key amino acids that improved sleep disturbances caused by brain injuries in mice - for millions of people affected by traumatic brain injury (TBI)—a condition that is currently untreatable.
Penn Medicine: Sleep-Deprived Mice Show Connections Among Lack of Shut-eye, Diabetes, Age
Sleep, or the lack of it, seems to affect just about every aspect of human physiology. Yet, the molecular pathways through which sleep deprivation wreaks its detrimental effects on the body remain poorly understood. Although numerous studies have looked at the consequences of sleep deprivation on the brain, comparatively few have directly tested its effects on peripheral organs.
Researchers at Penn Help Develop a Dynamic Model of Tissue Failure
The idea of growing replacement tissue to repair an organ, or to swap it out for an entirely new one, is rapidly transitioning from science fiction to fact.
Penn Med Team Reports on Study of First 59 Leukemia Patients Who Received Personalized Cellular Therapy
Three and a half years after beginning a clinical trial which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia will today announce the latest results of studies involving both adults and children with advanced blood cancers that have failed to respond to standard therapies.
Activating Pathway Could Restart Hair Growth in Dormant Hair Follicles, Penn Study Suggests
A pathway known for its role in regulating adult stem cells has been shown to be important for hair follicle proliferation, but contrary to previous studies, is not required within hair follicle stem cells for their survival, according to researchers with the Perelman School of Medicine at the University of Pennsylvania.
Researchers at Penn Show Optimal Framework for Heartbeats
The heart maintains a careful balancing act; too soft and it won’t pump blood, but too hard and it will overtax itself and stop entirely. There is an optimal amount of strain that a beating heart can generate and still beat at its usual rate, once per second.
Penn Study Treats Alzheimer’s by Delivering Protein Across Blood-Brain Barrier
The body is structured to ensure that any invading organisms have a tough time reaching the brain, an organ obviously critical to survival. Known as the blood-brain barrier, cells that line the brain and spinal cord are tightly packed, making it difficult for anything besides very small molecules to cross from the bloodstream into the central nervous system.
Penn’s Center for Tech Transfer Partners With British-based IP Group
The University of Pennsylvania, through its Center for Technology Transfer and its UPstart company formation program, has announced a new partnership with IP Group PLC, developer of intellectual property-based businesses.
Penn Emergency Medicine Physician Named as Director of the Federal Emergency Care Coordination Center
Brendan G. Carr, MD, MA, MS, assistant professor of Emergency Medicine and Epidemiology at the Perelman School of Medicine at the University of Pennslyvania, has been named as the director of the Emergency Care Coordination Center (ECCC).
In the News
Slate.com
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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The Hill
It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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The Wall Street Journal
The quest for treatments to keep weight off after Ozempic
Researchers at Penn are conducting a co-authored study of the brains, fat and muscle cells, and eating patterns of people trying to maintain new body sizes.
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Philadelphia Inquirer
Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Philadelphia Inquirer
Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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