Health Sciences

Memories Are ‘Geotagged’ With Spatial Information, Penn Researchers Say

Using a video game in which people navigate through a virtual town delivering objects to specific locations, a team of neuroscientists from the University of Pennsylvania and Freiburg University has discovered how brain cells that encode spatial information form “geotags” for specific memories and are activated immediately before those memories are recalled.

Evan Lerner

Penn Medicine: Targets of Anticancer Drugs Have Broader Functions than What Their Name Suggests

Drugs that inhibit the activity of enzymes called histone deacetylases (HDACs) are being widely developed for treating cancer and other diseases, with two already on the market. Researchers at the Perelman School of Medicine, University of Pennsylvania, show that a major HDAC still functions in mice even when its enzyme activity is abolished, suggesting that the beneficial effects of HDAC inhibitors may not actually be through inhibiting HDAC activity, and thus warranting the reassessment of the molecular targets of this class of drugs.

Karen Kreeger



In the News


Slate.com

What’s going on with tranq?

Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.

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The Hill

It’s time to end the Medicare-Medicaid merry-go-round

In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.

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The Wall Street Journal

The quest for treatments to keep weight off after Ozempic

Researchers at Penn are conducting a co-authored study of the brains, fat and muscle cells, and eating patterns of people trying to maintain new body sizes.

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Philadelphia Inquirer

Inside Penn’s transfer center

Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.

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Philadelphia Inquirer

Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use

Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.

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