News from

Bioengineering

Reset All Filters
177 Results
‘Leukemia-on-a-chip’ could transform CAR T blood cancer treatments
The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

(Image: NYU Tandon Applied Micro-Bioengineering Laboratory/Courtesy of Weiqiang Chen)

‘Leukemia-on-a-chip’ could transform CAR T blood cancer treatments

In a collaborative effort with NYU, Penn researchers have helped pioneer a novel 3D platform that mimics the human bone marrow and immune environment, enabling more predictive testing of cancer immunotherapy success in patients, including CAR T cell therapies.

3 min. read

Penn engineers turn toxic fungus into anti-cancer drug
Qiuyue Nie and Maria Zotova, from left, purify samples of the fungus in a lab.

First author Qiuyue Nie (left) and coauthor Maria Zotova purify samples of the fungus.

(Image: Bella Ciervo)

Penn engineers turn toxic fungus into anti-cancer drug

Penn-led researchers have isolated a new class of molecules from Aspergillus flavus, a toxic crop fungus, and modified it into a promising cancer-killing compound

Ian Scheffler

2 min. read

Decoding ancient immunity networks
Hand holding a blood vial that reads "complement (C3 + C4)"

A collaborative team from the School of Engineering and Applied Science and the Perelman School of Medicine have unraveled the mathematics of a 500-million-year-old protein network that acts like the body’s bouncer, “deciding” which foreign materials get degraded by immune cells and which are allowed entry.

(Image / iStock Md Saiful Islam Khan)

Decoding ancient immunity networks

A collaborative team from Penn Medicine and Penn Engineering have  unraveled the mathematics of a 500-million-year-old protein network that “decides” which foreign materials are friend or foe.

Nathi Magubane , Ian Scheffler , Holly Wojcik , Matt Toal

5 min. read

Delivering a one-two punch to superbugs to fight infections
Rakesh Krishnan sits at a computer staring at a 3D rendering of a protein.

Researchers led by César de la Fuente of the Perelman School of Medicine have created new peptides that fight hard-to-treat “superbug” infections by punching holes in bacterial cells and stimulating immune cells to signal for more defenders.

(Image: Courtesy of Jianing Bai) 

Delivering a one-two punch to superbugs to fight infections

Penn researchers create mirror-image molecules that both kill pathogens outright and rally the immune system—an advance aimed at the growing crisis of antimicrobial resistance.

3 min. read

AI x Science Postdoctoral Fellowship
Aerial shot of Amy Guttman Hall

Bhuvnesh Jain of the School of Arts & Sciences has teamed up with PIK University Professor René Vidal of the Perelman School of Medicine and the School of Engineering and Applied Science to create the AI x Science Fellowship offering postdoctoral researchers across the University opportunities to collaborate across disciplines.

nocred

AI x Science Postdoctoral Fellowship

Bhuvnesh Jain and René Vidal have teamed up to create the AI x Science Fellowship, which builds on the thriving postdoctoral program of the Data Driven Discovery Initiative to foster cross-disciplinary collaboration among researchers across the University.

6 min. read

Performer, biomedical engineer, and soon-to-be graduate
Jordyn Harris standing among lights

nocred

Performer, biomedical engineer, and soon-to-be graduate

A performer and dancer, fourth-year Jordyn Harris has been a work-study student for the Platt House and managed tech for myriad student shows, while also advising engineering first-years and working as a researcher at a hospital.

5 min. read