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Scientists unlock frogs’ antibacterial secrets to combat superbugs
An illustration of a frog.

The researchers theorized that frogs must have developed antibiotics to survive in their challenging environment.

(Image: Jianing “Jenny” Bai)

Scientists unlock frogs’ antibacterial secrets to combat superbugs

The lab of César de la Fuente has created synthetic peptides, a class of antibiotics, derived from the secretions of a frog commonly found in South Asia.

Ian Scheffler

2 min. read

Meniscus injuries may soon be treated by customizable hydrogel

Meniscus injuries may soon be treated by customizable hydrogel

Researchers at the Perelman School of Medicine found a new 3D-printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears, offering a potential mend for common joint injuries.

Frank Otto

1 min. read

Penn fourth-year Jaskeerat Gujral named 2025-2026 ThinkSwiss Research Scholar

Penn fourth-year Jaskeerat Gujral named 2025-2026 ThinkSwiss Research Scholar

Gujral, a fourth-year student in the College of Arts and Sciences studying neuroscience with a minor in chemistry, and sub-matriculating in the bioengineering master's program in the School of Engineering and Applied Sciences has been selected for a ThinkSwiss Research Scholarship, a program that aims to promote research opportunities in Switzerland to foster exchange between Swiss, U.S., and Canadian universities and research institutions.

From lab to classroom: The Center for Engineering MechanoBiology
Kayla Gay looking into a microscope in a lab.

Kayla Gay, who teaches middle school in Northwest Philadelphia, spent the summer learning about lab techniques that she can bring back to her classroom.

(Image: Courtesy of Kayla Gay)

From lab to classroom: The Center for Engineering MechanoBiology

Penn’s Center for Engineering Mechanobiology is a summer program for K-12 teachers in Philadelphia to work with scientists and engineers to develop innovative, hands-on lessons to engage students in STEM-integrated education.

Ian Scheffler

Building tomorrow’s innovators: Penn’s Widjaja Entrepreneurship Fellows Program
A group of students at Penn in class at a table.

David Bakalov, center, hopes to leverage his Fellows experience to develop new medical treatments.

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Building tomorrow’s innovators: Penn’s Widjaja Entrepreneurship Fellows Program

The Sugi and Millie Widjaja Engineering Entrepreneurship Fellows Program matches 12 Penn students with mentors to learn what it takes to transform ideas into potential companies.

Ian Scheffler

Stentix wins the 2025 Y-Prize
Winners of Penn’s 2025 Y-Prize holding their certificates.

The Stentix team (top) Summer Cobb and Amanda Kossoff, (bottom) Aarsha Shah and Elizabeth Jia, with judges (descending left) Matt Fitz-Henry, Jason Smith, Jennifer Gilburg, and Sasha Schrode, and (descending right) David Hsu, Gerald Lopez, and Dean Miller.

(Image: Courtesy of the William and Phyllis Mack Institute for Innovation Management)

Stentix wins the 2025 Y-Prize

The winning team of Penn Engineering’s annual award for entrepreneurial technology have created a noninvasive mechanism to adjust medical stent positioning using magnetic reconfiguration.

From the William and Phyllis Mack Institute for Innovation Management

Borrowing nature’s blueprint: How scientists replicated bone marrow
A chip with bioengineered bone marrow.

The new chip will allow for automated experiments, and can be connected to chip-based models of other organ systems, like the lungs.

(Image: Dan Huh)

Borrowing nature’s blueprint: How scientists replicated bone marrow

A collaborative research team from Penn Engineering, Penn Medicine, and the Children’s Hospital of Philadelphia have developed a chip that mimics human bone marrow.

Ian Scheffler

BEND lipids improve LNP mRNA delivery and gene editing
A gloved hand holding a beaker of lipids in a lab.

A sample of the new lipids, which improve the success rate of lipid nanoparticles delivering their contents.

(Image: Sylvia Zhang)

BEND lipids improve LNP mRNA delivery and gene editing

Penn Engineering researchers have developed a new class of lipids called branched endosomal disruptor (BEND) lipids to better deliver mRNA and gene-editing tools.

Ian Scheffler

Breakthroughs in gene editing and expression control with mvGPT
Tyler Daniel using a pipette in a bioengineering lab.

Sherry Gao, Tyler Daniel (pictured), and their coauthors have developed a new tool that can simultaneously and independently edit multiple genes and regulate their expression.

(Image: Bella Ciervo)

Breakthroughs in gene editing and expression control with mvGPT

Penn Engineers have created a gene editing tool that can address different genetic diseases in the same cell.

Ian Scheffler

Penn Center for Innovation celebrates 10 years
Scientists holding a model of something (forthcoming)

(Image: Eric Sucar)

Penn Center for Innovation celebrates 10 years

The University’s nexus for technology transfer supports researchers in their innovative efforts, from CAR T to mRNA advancements that have dramatically reshaped the world.