Engineers solve the paradox of why tissue gets stiffer when compressed

Tissue gets stiffer when it’s compressed. That stiffening response is a long-standing biomedical paradox, as common sense dictates that when you push the ends of a string together, it loosens tension, rather than increasing it. New research explains the mechanical interplay between that fiber network and the cells it contains.

Penn Today Staff

Bioengineers shed light on folding genomes

Jennifer Phillips-Cremins, an assistant professor in Penn Engineering’s Department of Bioengineering, and colleagues use light as a trigger to fold sequences of genes into specific shapes and patterns to see how the different configurations alter gene expression.

Penn Today Staff

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