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Bioengineering
Shedding light on cellular metabolism to fight disease
Shedding light on cellular metabolism to fight disease
In Yihui Shen’s lab, the assistant professor of innovation in bioengineering, aims to advance the understanding of metabolism and open doors to new cancer treatments and therapies.
Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles
Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles
New lipid platform enables rapid synthesis of molecules that can shuttle therapeutics for a range of diseases with a high degree of organ specificity.
Penn Engineering’s Ottman Tertuliano receives a 2024 CAREER Award
Penn Engineering’s Ottman Tertuliano receives a 2024 CAREER Award
Tertuliano’s research on bone fractures at the nanoscale allows for research on two separate time scales: the forming of cracks in a fracture at 1 micrometer/second, and the cellular response and repair time scale, a much lengthier process.
Penn third-year named 2024 Udall Scholar
Penn third-year named 2024 Udall Scholar
Third-year Joey Wu, studying bioengineering and environmental science in the Vagelos Integrated Program in Energy Research (VIPER) program, has been named a 2024 Udall Scholar.
A novel technique to form human artificial chromosomes
A novel technique to form human artificial chromosomes
Penn researchers say the new technique for making human artificial chromosomes from single, long constructs of designer DNA will allow for more efficient laboratory research.
Sherry Gao pushes the boundaries of genetic engineering
Sherry Gao pushes the boundaries of genetic engineering
The Presidential Penn Compact Associate Professor in Chemical and Biomolecular Engineering aims to make gene editing tools like CRISPR more accurate, and encourage first generation students along the way.
Accelerating CAR T cell therapy: Lipid nanoparticles speed up manufacturing
Accelerating CAR T cell therapy: Lipid nanoparticles speed up manufacturing
Penn Engineers have developed a novel method for manufacturing CAR T cells using lipid nanoparticles as delivery vehicles.
New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control
New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control
Penn Engineering researchers have invented a new way to synthesize the key chemical components of lipid nanoparticles that help protect and deliver medicinal payloads.
‘Switchable’ bispecific antibodies pave way for safer cancer treatment
‘Switchable’ bispecific antibodies pave way for safer cancer treatment
Immunotherapy utilizing an FDA-approved drug has enabled Penn researchers to develop a novel switchable bispecific T cell engager that mitigates negative outcomes of immunotherapy.
Illuminating the invisible: Bringing the smallest protein clusters into focus
Illuminating the invisible: Bringing the smallest protein clusters into focus
Penn engineers are opening new avenues for detecting the proteins implicated in diseases like Alzheimer’s and testing new treatments.
In the News
HealthDay
In mouse studies, new hope against a dangerous complication of pregnancy
Doctoral student Kelsey Swingle in the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication.
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New Scientist
Pre-eclampsia could be treated with mRNA technology
Michael Mitchell and Ph.D. student Kelsey Swingle of the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication.
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Axios
Real vs. fake Christmas trees: The great debate, explained
Lorena Grundy of the School of Engineering and Applied Science says that the debate between real and fake Christmas trees isn’t as black and white as it’s being portrayed.
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Rolling Stone
RFK Jr.’s 10 wildest medical theories
Kenneth R. Foster of the School of Engineering and Applied Science says studies haven’t provided clear evidence that exposure to levels of radio frequency energy below accepted limits, such as Wi-Fi, disrupts the blood-brain barrier.
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Nature
Gut microbes’ genomes are a trove of potential antibiotics
Marcelo Torres of the School of Engineering and Applied Science and colleagues are synthesizing antibiotic microbes from microbiomes in the human gut.
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Pittsburgh Post-Gazette
Smart meter debate: Small group of consumers pushes against a meter mandate in Pennsylvania
Kenneth Foster of the School of Engineering and Applied Science says that the most reliable conclusions are always those of expert panels that conduct systematic reviews according to established procedures.
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