Pathway behind muscle breakdowns in Duchenne muscular dystrophy discovered
An overactive genetic pathway in muscle stem cells was found to shorten the ends of chromosomes, called telomeres, resulting in DNA damage that impedes the normal healing response, according to a new study by researchers in Penn’s Perelman School of Medicine. The researchers believe this finding unveils the body’s origin point for the chronic muscle injuries associated with diseases like Duchenne muscular dystrophy.
FULL STORY AT Penn Medicine News →