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New genetic cause of blindness in dogs
Aguirre and Murgiano working in a lab with pipettes.

Gustavo D. Aguirre and Leonardo Murgiano of the School of Veterinary Medicine of the University of Pennsylvania.

(Image: John Donges)

New genetic cause of blindness in dogs

In collaboration with a foundation that breeds service dogs for the visually impaired, researchers at the School of Veterinary Medicine at the University of Pennsylvania and the University of Padova in Padova, Italy, have identified a novel variant associated with progressive retinal atrophy in three Labrador retrievers.

3 min. read

Older adults might be more resistant to bird flu infections than children
A petri dish in a lab labeled Avian Flu HSN4

Image: Digicomphoto via Getty Images

Older adults might be more resistant to bird flu infections than children

New research from Penn Medicine finds that previous exposures to older flu strains prime the immune system to produce antibodies against H5N1, and children would likely benefit the most from H5N1 vaccinations.

From Penn Medicine News

Getting to the root of root canals
Person receiving treatment in a dental clinic.

Image: Courtesy of Penn Dental Medicine/Peter Olson Photography

Getting to the root of root canals

Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.
Borrowing nature’s blueprint: How scientists replicated bone marrow
A chip with bioengineered bone marrow.

The new chip will allow for automated experiments, and can be connected to chip-based models of other organ systems, like the lungs.

(Image: Dan Huh)

Borrowing nature’s blueprint: How scientists replicated bone marrow

A collaborative research team from Penn Engineering, Penn Medicine, and the Children’s Hospital of Philadelphia have developed a chip that mimics human bone marrow.

Ian Scheffler

Celebrating five years of excellence at VinUniversity
Interim Penn President J. Larry Jameson in a lab examining a piece of equipment.

(Image: Courtesy of VinUniversity)

Celebrating five years of excellence at VinUniversity

Interim Penn President J. Larry Jameson visited VinUni in Hanoi, Vietnam, to commemorate the university’s fifth anniversary and Penn’s seventh year of allyship. He delivered a lecture about how excellent universities advance society.
New ways to modulate cell activity remotely
3D rendering of cells on a blue backdrop

Cells are dynamic, fast-changing, complex, tiny, and often hard-to-see in environments that don’t always behave in predictable ways when exposed to external stimuli. Now, researchers led by Lukasz Bugaj of the School of Engineering and Applied Science have found new ways to modulate cell activity remotely.

(Image: iStock/Maksim Tkachenko)

New ways to modulate cell activity remotely

Penn researchers use temperature to guide cellular behavior, promising better diagnostics and targeted therapies.
Developing kidneys from scratch
Rendering of kidneys.

Image: iStock/Vladyslav Severyn

Developing kidneys from scratch

Bioengineering professor Alex Hughes tackles the burden of chronic kidney disease by creating kidney tissue from scratch, which could reduce the need for both dialysis and transplantation.

Ian Scheffler