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RNA Toxicity Contributes to Neurodegenerative Disease, University of Pennsylvania Scientists Say
PHILADELPHIA –- Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans.
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Penn Vet World Awards Ceremony Provides $300,000 in Unrestricted Funding
What:Presentation of the First Penn Vet World Award and Penn Vet Student Inspiration AwardsWhere:Irvine Auditorium, University of Pennsylvania 3401 Spruce Street Philadelphia, PAWhen: 6:00 p.m., Tuesday, April 29, 2008 Reception immediately followingWho:
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Penn Students Vie for Top Prizes in Annual Invention Competition: PennVention
PHILADELPHIA –- The Weiss Tech House, a student-run hub of technological innovation at the University of Pennsylvania, announced today the 11 student inventions that will compete in the fourth annual PennVention competition.
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Penn Researchers Identify First Sex Chromosome Gene Involved in Meiosis and Male Infertility
PHILADELPHIA -– A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a particular sex chromosome meiosis-specific gene to sterility.
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Penn Scientists Find a Protein That Inhibits Ebola From Reaching Out to Infect Neighboring Cells
PHILADELPHIA -– Scientists at the University of Pennsylvania School of Veterinary Medicine have identified a protein, ISG15, that inhibits the Ebola virus from budding, the process by which viruses escape from cells and spread to infect neighboring cells. This study shows for the first time how ISG15 slows the spread of Ebola virus budding, an observation that could help explain how ISG15 successfully inhibits other viruses, including HIV-1 and herpes simplex virus type I.
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Penn Nursing Students Partner With Local High School to Evaluate Elementary Students' Health
PHILADELPHIA –- Students at West Philadelphia’s Sayre High School who are taking a health-education class have been working with University of Pennsylvania nurse practitioner students and Penn School of Nursing faculty to learn accurate growth and diabetes-risk-factor assessment.They are evaluating children in the Beacon after-school program at Sayre and providing nutrition education and a dance program designed to increase physical activity.
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Sarah Tishkoff Named Penn's Newest PIK Professor
PHILADELPHIA -– Sarah Tishkoff, a leading global expert in human genetics, has been named the sixth Penn Integrates Knowledge University Professor at the University of Pennsylvania.The announcement was made today by Penn President Amy Gutmann and Provost Ronald Daniels.
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Agent Orange Chemical, Dioxin, Attacks the Mitochondria To Cause Cancer, Says Penn Research Team
PHILADELPHIA— Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.
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Penn Researchers Shine the Light of Venus to Learn How the Herpes Virus Invades Cells
PHILADELPHIA -– University of Pennsylvania researchers have uncovered an important step in how herpes simplex virus, HSV-1, uses cooperating proteins found on its outer coat to gain entry into healthy cells and infect them. Further,the study’s authors say, they have demonstrated the effectiveness of monitoring these protein interactions using biomolecular complementation. The findings, published in the Proceedings of the National Academy of Sciences, provide a better understanding of the mechanism that viruses use to conquer healthy cells.
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University of Pennsylvania Researchers Zero In on the Tiniest Members in the War on Cancer
PHILADELPHIA -– Researchers from the University of Pennsylvania and Johns Hopkins University have uncovered another reason why one of the most commonly activated proteins in cancer is so dangerous. As reported in Nature Genetics this week, the Myc protein can stop the production of at least 13 microRNAs, small pieces of nucleic acid that help control which genes are turned on and off.