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Penn President Amy Gutmann’s record tenure of nearly 18 years is the University’s most transformative.
Two patients represent longest-known CAR T cell response to date, providing insight into treatment effect and outcomes.
Making up for the genetic mutations of MLL4 in skin cells, one of the most commonly mutated genes across all of human cancers, may keep epithelial cancer from beginning and progressing
An experimental immunotherapy can temporarily reprogram patients’ immune cells to attack heart fibroblast cells via only a single injection of mRNA.
A new Penn Medicine study finds that suppressing key exhaustion genes may allow CAR T cell treatments to be used much more effectively against pancreatic and other solid cancers.
The Cancer Clinical Trials Community Ambassador Training Program at the Abramson Cancer Center was established in August 2021 to create spokespersons and resources to increase awareness and access to cancer clinical trials in the diverse Philadelphia communities.
An injectable diagnostic illuminates cancer tissue that allows for greater precision during surgery was pioneered by surgeons at the University of Pennsylvania.
A team led by the School of Veterinary Medicine’s M. Andrés Blanco has uncovered a new target for treating certain blood cancers that works by removing an obstacle to their maturation.
Donald M. O’Rourke, director of the Glioblastoma Translational Center of Excellence at Penn Medicine, and others are exploring cellular immunotherapies as a potential better option for deadly brain cancer glioblastoma multiforme.
Focusing on neuroblastoma, researchers from the Perelman School of Medicine and Children’s Hospital of Philadelphia have harnessed the immune system to destroy tumors.
A 2020 study from the Perelman School of Medicine found that a blood test to screen for certain biomarkers associated with pancreatic cancer was 92% accurate in its ability to detect disease.
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A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.
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Penn Medicine researchers like Nobel laureate Drew Weissman are leading efforts to develop a vaccine that prevents cancer, with remarks from Susan Domchek of the Basser Center for BRCA and Robert H. Vonderheide of the Abramson Cancer Center.
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A trial led by Susan Domchek of the Perelman School of Medicine could use a preventive vaccine to protect people with a BRCA gene mutation from cancer.
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Daiwei Zhang and Mingyao Li of the Perelman School of Medicine and colleagues have developed an AI tool called iStar that can automatically spot tumors and types of cancer that are difficult for clinicians to see or identify and can predict candidates for immunotherapy.
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The Abramson Cancer Center is attempting to address one of the most common challenges cancer patients face: lack of transportation to critically important appointments. Robert Vonderheide and Carmen Guerra of the Perelman School of Medicine are quoted on the Ride Health initiative.
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