Investigational drug stops toxic proteins tied to neurodegenerative diseases
A Penn study finds that toxic proteins from mutated genes stimulate TDP-43 clumping, which can result in diseases like Lou Gehrig’s disease. Researchers also show that treatment with a pipeline drug known as an antisense oligonucleotide reduces the levels of such clumps, and the neurodegeneration that goes along with it.
FULL STORY AT Penn Medicine News →