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Successful Periodontal Therapy May Reduce the Risk of Preterm Birth, According to Penn Dental Study
PHILADELPHIA –- A collaboration led by a periodontal researcher from the University of Pennsylvania School of Dental Medicine has found a possible link between the success of gum-disease treatment and the likelihood of giving birth prematurely, according to a study published in the journal BJOG: An International Journal of Obstetrics and Gynaecology.
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Using the Structure of the Epidermal Growth Factor Receptor to Fight Cancer
PHILADELPHIA - Many types of tumors grow because of over-expression or a mutation of a protein called the epidermal growth factor receptor (EGFR), normally regulated by a hormone-like peptide called the epidermal growth factor (EGF). Several cancer drugs, including Herceptin, Erbitux, Iressa and Tarceva fight tumors by blocking EGFR and related receptors, notes Mark A.
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Dr. J. Larry Jameson to Lead Penn Medicine
PHILADELPHIA -- J. Larry Jameson, M.D., Ph.D., has been named the next executive vice president of the University of Pennsylvania for the Health System and dean of Penn’s School of Medicine, effective July 1, 2011. The announcement was made today by Penn President Amy Gutmann.
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Preventive Surgeries Linked to Lower Risk of Cancer for Women with BRCA1/2 Gene Mutations
Women who have inherited mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have substantially elevated risks of developing breast and ovarian cancer. A study that will appear in the September 1 issue of The Journal of the American Medical Association (JAMA) reports that women with these inherited mutations who have had a prophylactic mastectomy or salpingo-oophorectomy (removal of the fallopian tubes and ovaries) had an associated decreased risk of breast cancer and ovarian cancer.
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Violence in Inner City Neighborhoods Contributes to Trouble With Asthma
PHILADELPHIA – Patients with asthma who are exposed to violence in their community are at an increased risk for an asthma-related hospitalization and emergency room visits for asthma or any cause, according to new research from the University of Pennsylvania School of Medicine.
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Swimming Upstream: Molecular Approaches to Better Understand Male Infertility
Male infertility is a common medical problem, affecting millions of men in the United States annually. Its causes include an inability to make productive sperm. Now, using yeast as a model organism, researchers at the University of Pennsylvania School of Medicine are beginning to identify the molecular signals that could in part underlie that problem.Click here to view the full release.
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Genome Comparison of Ants Establishes New Model Species for Molecular Research
By comparing two species of ants, Shelley Berger, PhD, the Daniel S. Och University Professor at the University of Pennsylvania, and colleagues Danny Reinberg, PhD, New York University, and Juergen Liebig, PhD, Arizona State University, have established an important new avenue of research for epigenetics -- the study of how the expression or suppression of particular genes affects an organism's characteristics, development, and even behavior.
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Penn Study Sheds Light on How the Brain Transitions Between Sleep and Awake States Under Anesthesia
Despite the fact that an estimated 25 million patients per year in the U.S. undergo surgeries using general anesthesia, scientists have only been able to hypothesize exactly how anesthetics interact with the central nervous system. They previously thought that the processes of “going under” and waking up from anesthesia affected the brain in the same way.
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UMR Coalition Praises Recovery Act’s Investment Impact on Science, Innovation and Technology
PHILADELPHIA –- A White House report analyzing the impact of the American Recovery and Reinvestment Act on innovation, science and technology has drawn praise from United for Medical Research. UMR is a coalition of research institutions, patient and health advocates and private industry seeking steady increases in federal funding for the National Institutes of Health.
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Gene for Cholesterol and Cardiovascular Disease Identified through Genome Scan
Researchers at the University of Pennsylvania School of Medicine, the Broad Institute, Massachusetts General Hospital, and Alnylam Pharmaceuticals Inc., are some of the first to prove that a gene linked to a disease trait by genome wide association studies (GWAS) can be clinically relevant and an important determinant of disease risk.Click here to view the full release.