5/18
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Penn Scientists Identify New Role for Protein Molecule That Inhibits Response of Immune-System Cells
PHILADELPHIA -– Researchers at the University of Pennsylvania have identified a new role for a protein molecule that inhibits the response of immune-system cells to inflammatory signals associated with many human diseases.
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Penn Vet Announces $100,000 Winners of 2010 World Leadership Award and Student Inspiration Awards
PHILADELPHIA –- Mo Salman, professor of animal population health at Colorado State University, has been selected as the 2010 recipient of the Penn Vet World Leadership Award, given annually by the University of Pennsylvania School of Veterinary Medicine to a veterinarian who has dramatically changed the practice of the profession and influenced the lives of others.
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Hip Dysplasia Susceptibility in Dogs May Be Underreported, According to Penn Vet Comparative Study
PHILADELPHIA –- A study comparing a University of Pennsylvania method for evaluating a dog’s susceptibility to hip dysplasia to the traditional American method has shown that 80 percent of dogs judged to be normal by the traditional method are actually at risk for developing osteoarthritis and hip dysplasia, according to the Penn method.
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Researchers Find Clues to Gut Immunity Evolution, Reveal Similarities Between Fish/Humans
PHILADELPHIA -– A study at the University of Pennsylvania School of Veterinary Medicine has identified the function of one of the earliest antibodies in the animal kingdom, an ancient immunoglobulin that helps explain the evolution of human intestinal immune responses. It was discovered to play a predominant role in the guts of fish and paves the way for a better understanding of human gut immunity as well as for safer, healthier approaches to keeping fish from pathogen infections. The findings appear in the online version of
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Collaboration Solves Structure of Herpes Virus Protein, Provides New Drug Directions
PHILADELPHIA -– The mechanism by which a herpes virus invades cells has remained a mystery to scientists, but now research from Tufts University and the University of Pennsylvania reveals the unusual structure of a key member of the protein complex that allows a herpes virus to invade cells.The new map details an essential piece of the herpes virus “cell-entry machinery,” providing scientists with a new target for antiviral drugs.
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Seven in School of Veterinary Medicine Honored With Teaching Awards
Seven faculty members in the University of Pennsylvania School of Veterinary Medicine are recipients of 2010 teaching awards.
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Gene Therapy Success Sets Stage for New Treatments for Inherited Blindness, Penn Veterinary Researchers Say
PHILADELPHIA –- Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by rod degeneration.
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Gene Therapy Cures Canines of Inherited Form of Day Blindness, Penn Veterinary Researchers Say
PHILADELPHIA –- Veterinary ophthalmology researchers from the University of Pennsylvania have used gene therapy to restore retinal cone function and day vision in two canine models of congenital achromatopsia, also called rod monochromacy or total color blindness.
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Double Agents: Penn Researchers Identify Immune Cells That Fight Parasites May Promote Allergies and Asthma
PHILADELPHIA –- Millions of people in both the developing and developed world may benefit from new immune-system research findings from the University of Pennsylvania School of Veterinary Medicine.The Penn Vet researchers, studying how the immune system operates, have discovered a previously unidentified cell population that may be the body’s double-edged sword, fighting off parasitic infections but also causing the harmful immune responses that can lead to allergies and asthma.
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Penn Researchers Find Reproductive Germ Cells Survive and Thrive In Transplants, Even Among Species
PHILADELPHIA –- Reproductive researchers from the University of Pennsylvania and The Children’s Hospital of Philadelphia have succeeded in isolating and transplanting pure populations of the immature cells that enable male reproduction in two species—human spermatogonia and mouse gonocytes. These germline stem cells, taken from testis biopsies, demonstrated viability following transplantation to mouse testes within a controlled laboratory setting.