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RNA is both the bridge between DNA and the production of proteins that carry out the functions of life and what guides which and how much protein gets made.
Once again, researchers at Penn’s Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.
The PD-1 inhibitor pembrolizumab, a cancer immunotherapy drug, shrank or halted growth of tumors in 76 percent of patients with pleural mesothelioma, a rare and deadly form of cancer that arises in the outer lining of the lungs and internal chest wall, according to a new study from researchers in the Perelman School of Medicine at the Unive
Genetically modified versions of patients’ own immune cells successfully traveled to tumors they were designed to attack in an early-stage trial for mesothelioma and pancreatic and ovarian cancers at the Perelman School of Medicine at the University of Pennsylvania.
Building on previous research showing that plasma Apolipoprotein A1 (ApoA1) may be a useful biomarker for Parkinson’s disease, researchers from the Perelman School of Medicine at the University of Pennsylvania have replicated these findings in approximately 1,000 patients from across the world, upholding their
Brain researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a new brain mapping model which could improve the success rate of transcranial magnetic stimulation (TMS) in treating conditions including depression, neuropathic pain, and stroke.
Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves.
Donita Brady has been named the seventh Presidential Professor at the University of Pennsylvania, effective July 1. She will be Presidential Assistant Professor of Cancer Biology in Penn’s Perelman School of Medicine.
Emergency department patients have misperceptions about opioid dependence and want more information about their pain management options, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine says that Neanderthal DNA provides insights into human evolution, population dynamics, and genetic adaptations, including correlations with traits such as immunity and susceptibility to diseases.
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According to Aditi Vasan of the Leonard Davis Institute and Perelman School of Medicine, evidence is mounting in favor of the model of training community health workers to help their neighbors connect to government and health care services.
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According to Thomas Wadden of the Perelman School of Medicine, people taking GLP-1 drugs are finding that daily experiences that used to trigger a compulsion to eat or think about food no longer have that effect.
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PIK Professor Ezekiel Emanuel says that incessantly preparing for old age mistakes a long life for a worthwhile one.
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Shoshana Aronowitz of the School of Nursing and Ashish Thakrar of the Perelman School of Medicine comment on the lack of specificity in Philadelphia’s plan to remove drug users from Kensington and on the current state of drug treatment in the city.
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