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Genetic switch turns tumor suppressor into oncogene in colorectal cancer
Fluorescent microscopy of colon cancer cells..

(Image: Yuhua Tian)

Genetic switch turns tumor suppressor into oncogene in colorectal cancer

Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.

Liana F. Wait

Shifting the climate narrative
The sky glows yellow and purple after a strong summer storm in Philly.

On Sept. 12, PBS, WHYY, and the Penn Center for Science, Sustainability and the Media are set to gather a group of community leaders, journalists, science communicators, and scientists to explore the role of storytelling in climate change education.

(Image: iStock / Luke Chen)

  • Q&A

    • Shifting the climate narrative

    In a Q&A with Penn Today, Michael Mann of the Penn Center for Science, Sustainability, and the Media shares his views on the role of storytelling in the fight against climate change.
    The new U.S. plan to target xylazine-laced fentanyl
    Two hands wearing latex gloves wrapping a bandage on a wound.

    Image: Volodymyr for Adobe Stock

    The new U.S. plan to target xylazine-laced fentanyl

    Researchers from Penn LDI, in conjunction with the Center for Health Economics of Treatment Interventions for Substance Use Disorder, analyze the plan and raise the question of whether it goes far enough.

    From Penn LDI

    Duo of exhibitions showcase ‘Moveables’ and portraiture
    Love seats and side tables placed in front of arched mirrors.

    One of three furniture pieces by Ken Lum, a featured artist in the “Moveables” exhibit at the ICA.

    nocred

    Duo of exhibitions showcase ‘Moveables’ and portraiture

    “Moveables” and “When the Children Come Home” are the latest exhibits on display at the Institute of Contemporary Art, which remains free to all.
    A historian’s look at the ‘illusions of progress’
    Man in laborer clothes holds shovel, smokes a pipe and looks at his paycheck by a sign reading "USA Work Program WPA"

    A Works Progress Administration worker receives his paycheck, 1939.

    (Image: Courtesy of the National Archives)

    A historian’s look at the ‘illusions of progress’

    A new book by historian Brent Cebul looks at the successes and failures of American liberalism, from the New Deal to the 1990s and beyond.

    Kristen de Groot

    A link between memory and appetite in the brain to explain obesity
    rendering of a brain and its different sections highlighted as different colors.

    Image: iStock/Floaria Bicher

    A link between memory and appetite in the brain to explain obesity

    Penn Medicine researchers have found the hippocampal subnetwork, located within the memory center of the brain, is more dysregulated in patients with higher body mass indexes, leading to an inability to control or regulate eating habits.

    Kelsey Geesler

    Social ecology and community work in the Galápagos
    students studying the galapagos, sitting on waterfront

    (On homepage) On a Penn Global Research Institutes outing to Tortuga Bay, students and Penn Global’s Laurie Jensen sit on rocks in a lava field overlooking a hypersaline pool.

    (Image: Michael Weisberg)

    Social ecology and community work in the Galápagos

    Undergraduate and graduate students spent two months on San Cristóbal Island this summer, doing research on antibacterial resistance, vectors of disease, climate change adaptation, and the impact of climate change on mental health.
    Paul Farber on the Monument Lab and public art
    An installation on the National Mall.

    Wendy Red Star, The Soil You See..., 2023, from Beyond Granite on the National Mall in Washington, DC.

    (Image: AJ Mitchell/Courtesy of Monument Lab)

    Paul Farber on the Monument Lab and public art

    The Penn alum and co-founder of Monument Lab offers a behind-the-scenes look at the new public art installation curated by Monument Lab on the National Mall.

    From the Weitzman School of Design