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Perelman School of Medicine
Deciphering Hidden Code Reveals Brain Activity
By combining sophisticated mathematical techniques more commonly used by spies instead of scientists with the power and versatility of functional magnetic resonance imaging (fMRI), a Penn neurologist has developed a new approach for studying the inner workings of the brain.
Researchers Explore Conflicts of Interest in Development of Cardiovascular Practice Guidelines
A new analysis by researchers at the University of Pennsylvania School of Medicine of recent cardiology clinical practice guidelines has found that more than half of the experts involved in the development of these guidelines reported a conflict of interest (COI).
Penn Researchers Uncover Novel Immune Therapy for Pancreatic Cancer
Researchers at the University of Pennsylvania’s Abramson Cancer Center have discovered a novel way of treating pancreatic cancer by activating the immune system to destroy the cancer’s scaffolding. The strategy was tested in a small cohort of patients with advanced pancreatic cancer, several of whose tumors shrank substantially.
Rocking the Vote from Rocking Chairs
For seniors, voting can be difficult: standing with a walker or cane in the voting booth, struggling to read the tiny print on the ballot or trying to punch the tiny button to vote for the intended candidate. Despite the desire to vote, the typical voting process leaves many seniors disenfranchised, particularly for residents of long term care facilities.
Mouse Nose Nerve Cells Mature After Birth, Allowing Bonding, Recognition With Mother, Penn Study Finds
For rodent pups, bonding with mom isn’t hard-wired in the womb. It develops over the first few weeks of life, which is achieved by their maturing sense of smell, possibly allowing these mammals a survival advantage by learning to identify mother, siblings, and home.
Molecules Work the Day Shift to Protect the Liver from Accumulating Fat, Says Penn Study
The liver normally makes and stores fat, which is required in moderation for normal body function. However, if the process goes awry, excess fat in the liver can cause major liver damage. In fact, fatty liver is a leading cause of liver failure in the United States, and is often brought on by obesity and diabetes.
Penn Medicine Expert Rethinking Medicare Hospice Eligibility Criteria
When Medicare hospice eligibility criteria expand in 2011 as part of the Affordable Care Act of 2010, efforts to test whether palliative care and aggressive treatment provided concurrently will be judged based on costs.
Penn Study: 'GPS System' for Protein Synthesis in Nerve Cells Gives Clues for Understanding Brain Disorders
Scientists at the University of Pennsylvania explain how a class of RNA molecules is able to target the genetic building blocks that guide the functioning of a specific part of the nerve cell. Abnormalities at this site are in involved in epilepsy, neurodegenerative disease, and cognitive disorders.
13 Novel Genetic Components of Coronary Artery Disease Identified
An international analysis of 14 genome-wide association studies involving over 100,000 patients has identified 13 new genetic risk factors for coronary artery disease (CAD).
New Findings on Drug Tolerance in Tuberculosis Suggest Ideas for Shorter Cures
New research on how tuberculosis (TB) bacteria develop multi-drug tolerance points to ways TB infections might be cured more quickly. The study was published online last week in Cell.
In the News
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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