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Perelman School of Medicine
Penn Researchers Find New Role for Cancer Protein p53
PHILADELPHIA - The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins.
Call for Medical Schools to Teach Students Health Policy Issues Facing Patients
PHILADELPHIA -- How would you like your car to be fixed by someone who had no knowledge of what it was like to drive?
First International Collaboration on the Genetics of Alzheimer's Disease Is Launched
The launch of the International Genomics of Alzheimer’s Project (IGAP) – a collaboration formed to discover and map the genes that contribute to Alzheimer’s disease – was announced Feb. 1 by a multi-national group of researchers.
Penn Researcher Receives $2 million From NIH to Test Macular Degeneration Drug
John Lambris, PhD, the Dr.
Immune Cells Protect Body from Invaders, According to Penn Researchers
PHILADELPHIA - So-called barrier sites -- the skin, gut, lung – limit the inner body’s exposure to allergens, pollutants, viruses, bacteria, and parasites. Understanding how the immune system works in these external surfaces has implications for understanding such inflammatory diseases as asthma, psoriasis, IBD, and food allergies, all of which occur at the body’s barriers.
Sideline Test Accurately Detects Athletes’ Concussions in Minutes, Penn Study Shows
PHILADELPHIA – A simple test performed at the sideline of sporting events can accurately detect concussions in athletes, according to study by researchers at the University of Pennsylvania School of Medicine. Current sideline tests can leave a wide amount a brain function untested following concussion.
New Study from Penn Medicine: Antidepressant Use Reduced Hot Flashes in Menopausal Women
“Our findings suggest that among healthy women who were not depressed or anxious, a 10 to 20 milligram dose of escitalopram – which is well below the dosage level for psychiatric use – provides a nonhormonal, off-label option that is effective and well-tolerated in the management of menopausal hot flashes,” said Elle
Researchers Uncover New Gene for Heart Failure in Caucasians
Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge.
Certain Genetic Profiles Increase Risk of Coronary Artery Disease, While Others Increase Risk of Heart Attack
(PHILADELPHIA) – Coronary artery disease (CAD) is the single largest cause of death in adults in the United States. Until recently, the genetic basis of CAD has been largely unknown, with just a few proven genes (typically genes for cholesterol disorders) accounting for very little of the disease in the population.
Penn Study Shows New Measure Trumps HDL Levels in Protecting Against Heart Disease
(PHILADELPHIA) – The discovery that high levels of high-density lipoprotein (HDL) cholesterol (the “good cholesterol”) is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain.
In the News
Slate.com
What’s going on with tranq?
Jeanmarie Perron of the Perelman School of Medicine says that the appearance and progression of skin ulcers and tissue loss on xylazine users is different than with other intravenous drugs.
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The Hill
It’s time to end the Medicare-Medicaid merry-go-round
In an opinion essay, Rachel M. Werner of the Leonard Davis Institute, Wharton School, and Perelman School of Medicine says that Medicare and Medicaid fail to integrate coverage and coordinate care across their two plans.
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Philadelphia Inquirer
Inside Penn’s transfer center
Penn Medicine’s transfer command center gets patients from affiliated hospitals and hospitals outside Philadelphia to specialized care that can save lives, with comments from CEO Kevin Mahoney.
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Philadelphia Inquirer
Operating rooms are major sources of greenhouse gasses. Penn is eliminating a form of anesthesia that hangs in the air for more than a decade after use
Penn Medicine is phasing out the anesthesia desflurane at four of its six hospitals to eliminate harmful greenhouse gases, with remarks from Greg Evans.
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Philadelphia Inquirer
Broad Street runners from Penn are racing with gyroscopes to study the Achilles tendon
Casey Jo Humbyrd and Josh Baxter of the Perelman School of Medicine and colleagues will track data from running the Broad Street Run to understand how a healthy Achilles tendon functions.
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