Health Sciences

Patch or Pills? How Quickly Smokers Metabolize Nicotine May Point to Most Effective Way to Quit, Penn Study Finds

Nearly 70 percent of smokers who try to quit relapse within one week – daunting odds for people trying to kick the habit. Researchers have long theorized that some individuals may be genetically programmed to have an easier time than others, but with few clues about why, experts have been unable to guide smokers looking to quit toward a strategy – the nicotine patch versus prescription pills, for instance – with the best chance of success.

Steve Graff

Penn Study: Overly Conservative FDA Label Likely Prevents Use of Metformin in Many Type 2 Diabetics

Many patients with type 2 diabetes in the United States may be discouraged from taking metformin—a proven, oral diabetes medicine—because the U.S. Food and Drug Administration inappropriately labels the drug unsafe for some patients also suffering from kidney problems, researchers from Penn Medicine and Weill Cornel Medical College report this week in a research letter published in JAMA Internal Medicine.

Steve Graff

Penn Scientists Identify Patterns of RNA Regulation in the Nuclei of Plants

When the human genome was first sequenced, experts predicted they would find about 100,000 genes. The actual number has turned out to be closer to 20,000, just a few thousand more than fruit flies have. The question logically arose: how can a relatively small number of genes lay the blueprint for the complexities of the human body?

Katherine Unger Baillie



In the News


The New York Times

‘This is a dangerous virus’

According to Louise Moncla of the School of Veterinary Medicine, reinfections suggest that the H5N1 bird flu virus could circulate on farms indefinitely, creating opportunities for it to evolve into a more dangerous form.

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Interesting Engineering

Scientists create tiny anticancer weapons that make tumors destroy themselves

Xiaowei (George) Xu of the Perelman School of Medicine and colleagues have unveiled an innovative approach to cancer treatment that leverages tiny capsules known as small extracellular vesicles to target a specific receptor on tumor cells.

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6ABC.com

Bird flu suspected in deaths of 200 snow geese in Pennsylvania’s Lehigh Valley

Stephen Cole of the School of Veterinary Medicine says that indoor cats are contracting bird flu through raw pet foods of poultry origin or raw milk products.

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NPR

Tuberculosis rates plunge when families living in poverty get a monthly cash payout

Aaron Richterman of the Perelman School of Medicine says that there are large and underappreciated benefits of cash-transfer programs, such as potentially ending a tuberculosis epidemic.

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Self

The surgeon general calls for new warning labels on alcohol—here’s the truth about how it impacts your health

Henry Kranzler of the Perelman School of Medicine says that alcohol’s effects on the brain are observed more readily because it’s the organ of behavior.

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