11/15
Cancer Research
Secondary cancers following CAR T cell therapy are rare
Secondary cancers following CAR T cell therapy are rare
A new Penn Medicine analysis shows that the development of any type of second cancer is a rare occurrence, and some of the earliest patients have gone on to experience long-lasting remissions of a decade or more.
New AI tool brings precision pathology for cancer into quicker, sharper focus
New AI tool brings precision pathology for cancer into quicker, sharper focus
Researchers at Penn Medicine have developed an artificial intelligence tool to quickly analyze gene activities in medical images and provide single-cell insight into diseases in tissues and tissue microenvironments.
Lidocaine may be able to kill certain cancer cells by activating bitter taste receptors
Lidocaine may be able to kill certain cancer cells by activating bitter taste receptors
A preclinical Penn Medicine study explains the previously observed anti-cancer effect of the common anesthetic drug.
Decentralizing cancer screenings
Decentralizing cancer screenings
A Projects for Progress team in the Abramson Cancer Center continues to work with the West Philadelphia community to bring cancer screenings out of clinical settings.
Penn Medicine studies unlock new insights into gene therapy
Penn Medicine studies unlock new insights into gene therapy
The studies on AAV-based gene therapies in non-human primates suggest that integration into human DNA is unlikely to drive cancer mutations.
How cell developmental biology fits into the future of medicine
How cell developmental biology fits into the future of medicine
Ben Stanger, the Hanna Wise Professor in Cancer Research and professor of medicine and cell and developmental biology, discusses his research and publishing his first book, ‘From One Cell: A Journey into Life’s Origins and the Future of Medicine.’
A ‘thermometer’ tool to measure tumor growth between scans
A ‘thermometer’ tool to measure tumor growth between scans
Researchers at Penn Medicine have developed a first-ever tool that gives a real-time assessment of tumors to provide less uncertainty for patients worrying between scans.
Leveraging the body’s postal system to understand and treat disease
Leveraging the body’s postal system to understand and treat disease
An interdisciplinary team of researchers in the School of Engineering and Applied Science, Perelman School of Medicine, and School of Arts & Sciences has developed a technique that allows for characterization of both individual carrier and cargo for clinically important molecules.
Study shows promise for iNKT cell platform to treat cancer
Study shows promise for iNKT cell platform to treat cancer
Researchers from the School of Veterinary Medicine and Perelman School of Medicine have shown that invariant natural killer T cells from a healthy donor can persist in MHC-mismatched canines, demonstrating a reliable platform to inform human clinical trials.
Removing the barrier surrounding solid tumors clears path for T cells
Removing the barrier surrounding solid tumors clears path for T cells
Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.
In the News
Forbes
Carl June: 2024 will be seen as a breakthrough year for brain cancer
Carl June of the Perelman School of Medicine shares five insights on using CAR T cell therapy to combat cancer, featuring remarks from Bruce Levine.
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Philadelphia Inquirer
Penn plans to build a proton center for cancer treatment at Presbyterian Medical Center
Penn Medicine will build its fourth proton beam center for cancer treatment at Penn Presbyterian Medical Center in University City.
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PhillyVoice
Double mastectomies do not improve breast cancer survival likelihood for most women, study finds
Angela DeMichele of the Perelman School of Medicine says that chemotherapy and hormonal therapies are important for combating breast cancer because they’re designed to kill spreading cells.
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The New York Times
Breast cancer survival not boosted by double mastectomy, study says
Angela DeMichele of the Perelman School of Medicine comments on a study which found that breast cancer survival is not boosted by a double mastectomy.
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Today
How did Shannen Doherty die? What to know about ‘90210’ star’s cause of death
According to Penn Medicine, there is no known cure for metastatic breast cancer.
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Stat
New immunotherapy combination could ‘change the landscape’ of cancer treatment
A study by Andy Minn and postdoc Divij Mathew of the Perelman School of Medicine and colleagues found that a combination checkpoint inhibitor therapy benefited patients with lung cancer.
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