Cancer Research | Penn Today

Emily Whitehead was the first child cured of cancer with therapy from Penn. She’s back as a freshman

Emily Whitehead of Philipsburg, Pennsylvania, the first child cured of leukemia with CAR-T cancer therapy, has returned to Penn as a first-year in the College of Arts and Sciences.

A ‘thermometer’ tool to measure tumor growth between scans

Researchers at Penn Medicine have developed a first-ever tool that gives a real-time assessment of tumors to provide less uncertainty for patients worrying between scans.

Isolated microfluidic chip with blood sample inside of micropipette 3d rendered in the black background

Leveraging the body’s postal system to understand and treat disease

An interdisciplinary team of researchers in the School of Engineering and Applied Science, Perelman School of Medicine, and School of Arts & Sciences has developed a technique that allows for characterization of both individual carrier and cargo for clinically important molecules.

Study shows promise for iNKT cell platform to treat cancer

Researchers from the School of Veterinary Medicine and Perelman School of Medicine have shown that invariant natural killer T cells from a healthy donor can persist in MHC-mismatched canines, demonstrating a reliable platform to inform human clinical trials.

Vampiric cancer cells, a brain atlas, & alleged misconduct at Cassava

Research by Bo Li of the Perelman School of Medicine finds that cancer cells can use mitochondria to sap energy from T cells, resisting treatment and evading the body’s defenses.

Why CAR T cell therapy is the cancer killer the world needs now

Research from Michael Mitchell of the School of Engineering and Applied Science has developed a new method to stop cytokine release during CAR T cell therapy, preventing some of its more dangerous side effects.

Stroma-targeting CAR T cells (green) in the stroma surrounding a solid tumor.

Removing the barrier surrounding solid tumors clears path for T cells

Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.

Penn’s cell therapy pioneer Dr. Carl June shares $3M Breakthrough Prize in Life Sciences

Carl June of the Perelman School of Medicine has been awarded a $3 million Breakthrough Prize in life sciences for developing CAR-T therapy to treat cancer, with remarks from President Liz Magill.

Penn’s Carl June splits a $3 million Breakthrough Prize for pioneering the cancer treatment CAR-T

Carl June of the Perelman School of Medicine has been honored with the $3 million Breakthrough Prize for discovering how to attack cancer by harnessing a patient’s immune system through CAR-T therapy.

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