Cancer Research

How mRNA vaccines help fight cancer tumors

Penn researchers are looking to mRNA vaccines for applications outside of infectious diseases, as they can not only prompt strong antibody responses to fight off invaders, like COVID-19, but also potent cytotoxic T cell responses.

Steve Graff

Black and white women have same mutations linked to breast cancer risk

The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, but the takeaway is not to change testing guidelines based on race alone, but focus on ensuring equal access to and uptake of testing to minimize disparities in care and outcomes.

Steve Graff

COVID’s impact on cancer care comes more into focus

With the disruption of cancer care since the pandemic began in March 2020, recent reports are starting to show that the interruption—while still significant—may not be as detrimental as experts originally feared.

Steve Graff

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In the News

Philadelphia Inquirer

More Black patients are participating in clinical trials for cancer treatment at Penn thanks to this effort

Carmen Guerra and Armenta Washington of the Abramson Cancer Center spoke about their efforts to enroll more Black patients with cancer in clinical trials. “When we conduct research, we want to say that what we learn applies to all people,” said Guerra. “But that might not be the case if we are just studying one population.”


CBS News

Cancer Moonshot project launched by President Biden 5 years ago leading to many breakthroughs

Robert Vonderheide of Penn’s Abramson Cancer Center in the Perelman School of Medicine spoke about the Cancer Moonshot project, which has led to major federal funding for cancer research and subsequently, new treatments for patients. “It’s new initiatives, new therapies, and new ways importantly to prevent cancer in the first place,” he said.


The Washington Post

For those at risk for cancer, weighing the risk of COVID-19 with delays in screening and treatment

Lawrence Shulman of the Perelman School of Medicine says declining numbers of new cancer diagnoses over the past four months don’t mean fewer people actually have cancer. “There are a lot of patients out there who have cancer but are not undergoing diagnosis and entry into the cancer care system,” he said.


New Scientist

CRISPR cancer trial finds that gene-edited immune cells are safe

Edward Stadtmauer and Carl June of the Perelman School of Medicine spoke about a clinical trial that found it safe to inject CRISPR gene-edited immune cells into people with advanced cancer.



Deciphering a cancer treatment’s dark side

Saar Gill of the Perelman School of Medicine said it would be easier to treat cancer using CAR-T cell therapy without the looming possibility of triggering cytokine release syndrome.


Scientific American

Could immunotherapy treat diseases besides cancer?

Jonathan Epstein of the Perelman School of Medicine is quoted on how immunotherapy has transformed cancer care.