2/21
Cancer Research
No evidence that CAR T cell therapy causes secondary cancers
No evidence that CAR T cell therapy causes secondary cancers
In a new study, researchers at Penn Medicine looked for—and did not find—examples where the process of generating CAR T cells caused malignancy.
The compassionate team behind CAR T cancer breakthroughs
The compassionate team behind CAR T cancer breakthroughs
The clinical trial support staff at Penn Medicine and the Abramson Cancer Center have helped execute the team science that brings research discoveries from the lab bench to the bedside.
New ways to modulate cell activity remotely
New ways to modulate cell activity remotely
Penn researchers use temperature to guide cellular behavior, promising better diagnostics and targeted therapies.
Developing a tiny anticancer weapon
Developing a tiny anticancer weapon
Penn Medicine researchers have developed tumor-homing nanosized particles that trigger cancer cell self-destruction in preclinical tests.
Discovery links cellular structures to kidney cancer treatment outcomes
Discovery links cellular structures to kidney cancer treatment outcomes
New research from Penn Medicine finds patterns in cells of tumors may guide personalized therapies for clear cell renal cell carcinoma.
New tool puts reproductive risk for BRCA carriers into perspective
New tool puts reproductive risk for BRCA carriers into perspective
A team at Penn Medicine has created a resource to help inform reproductive counseling for cancer gene mutation carriers.
Generic platinum chemotherapy shortages did not increase deaths
Generic platinum chemotherapy shortages did not increase deaths
A national data analysis finds that short-term mortality was not impacted by the shortage for patients with advanced cancers.
Brain tumor organoids accurately model patient response to CAR T cell therapy
Brain tumor organoids accurately model patient response to CAR T cell therapy
Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to researchers at Penn Medicine.
Keto diet metabolite may power up CAR T cells to kill cancer
Keto diet metabolite may power up CAR T cells to kill cancer
Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy.
Easing patient fears of radiation treatment, via virtual reality
Easing patient fears of radiation treatment, via virtual reality
Before their first dose of radiation, cancer patients can shadow another patient’s treatment and get a private behind-the-scenes tour with the team members via virtual reality.
In the News
Interesting Engineering
Scientists create tiny anticancer weapons that make tumors destroy themselves
Xiaowei (George) Xu of the Perelman School of Medicine and colleagues have unveiled an innovative approach to cancer treatment that leverages tiny capsules known as small extracellular vesicles to target a specific receptor on tumor cells.
FULL STORY →
HealthDay
Keto diet supplement could boost a cancer treatment's effectiveness
A study by Perelman School of Medicine student Puneeth Guruprasad and postdoc Shan Liu suggests that a component of the keto diet could boost CAR T cell therapy to help treat cancer.
FULL STORY →
Forbes
Carl June: 2024 will be seen as a breakthrough year for brain cancer
Carl June of the Perelman School of Medicine shares five insights on using CAR T cell therapy to combat cancer, featuring remarks from Bruce Levine.
FULL STORY →
Philadelphia Inquirer
Penn plans to build a proton center for cancer treatment at Presbyterian Medical Center
Penn Medicine will build its fourth proton beam center for cancer treatment at Penn Presbyterian Medical Center in University City.
FULL STORY →
PhillyVoice
Double mastectomies do not improve breast cancer survival likelihood for most women, study finds
Angela DeMichele of the Perelman School of Medicine says that chemotherapy and hormonal therapies are important for combating breast cancer because they’re designed to kill spreading cells.
FULL STORY →
The New York Times
Breast cancer survival not boosted by double mastectomy, study says
Angela DeMichele of the Perelman School of Medicine comments on a study which found that breast cancer survival is not boosted by a double mastectomy.
FULL STORY →