Cancer Research | Penn Today

Scientists create tiny anticancer weapons that make tumors destroy themselves

Xiaowei (George) Xu of the Perelman School of Medicine and colleagues have unveiled an innovative approach to cancer treatment that leverages tiny capsules known as small extracellular vesicles to target a specific receptor on tumor cells.

Developing a tiny anticancer weapon

Penn Medicine researchers have developed tumor-homing nanosized particles that trigger cancer cell self-destruction in preclinical tests.

Discovery links cellular structures to kidney cancer treatment outcomes

New research from Penn Medicine finds patterns in cells of tumors may guide personalized therapies for clear cell renal cell carcinoma.

A pregnant person meeting with their doctor.

New tool puts reproductive risk for BRCA carriers into perspective

A team at Penn Medicine has created a resource to help inform reproductive counseling for cancer gene mutation carriers.

Generic platinum chemotherapy shortages did not increase deaths

A national data analysis finds that short-term mortality was not impacted by the shortage for patients with advanced cancers.

Microscopic view of a glioblastoma organoid.

Brain tumor organoids accurately model patient response to CAR T cell therapy

Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to researchers at Penn Medicine.

2 min. read

3-D rendering of chimeric antigen receptor T (CAR-T) cell therapy, a treatment for a variety of cancers

Keto diet metabolite may power up CAR T cells to kill cancer

Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy.

Keto diet supplement could boost a cancer treatment's effectiveness

A study by Perelman School of Medicine student Puneeth Guruprasad and postdoc Shan Liu suggests that a component of the keto diet could boost CAR T cell therapy to help treat cancer.

People holding VR headsets at a display table.

Easing patient fears of radiation treatment, via virtual reality

Before their first dose of radiation, cancer patients can shadow another patient’s treatment and get a private behind-the-scenes tour with the team members via virtual reality.

White House names Abramson Cancer Center neuro-oncologist a Cancer Moonshot Scholar

Richard E. Phillips, chief of the division of Neuro-Oncology and an assistant professor of neurology, is among 11 scholars included in this year’s cohort, who will support cancer research and innovation across the country.

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