Through
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Cancer Research
Why cancers caused by BRCA mutations recur
Why cancers caused by BRCA mutations recur
Findings from Penn Medicine uncover possible drivers of recurrent breast and ovarian cancers among women carrying high-risk genetic mutations, pointing to methods to more effectively treat disease.
A FLASH of radiation may pave the way toward new cancer care for people and pets alike
A FLASH of radiation may pave the way toward new cancer care for people and pets alike
Led by the Perelman School of Medicine’s Keith Cengel and the School of Veterinary Medicine’s Brian Flesner, a new study is evaluating the safety and efficacy of treating oral cancer in dogs with a palliative radiation in just two clinic visits.
NIH-funded canine immunotherapy data center charts a path toward transformative therapies
NIH-funded canine immunotherapy data center charts a path toward transformative therapies
With support recently granted for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new insights in cancer care for people as well as pets.
Eight Penn scientists receive NIH grants through High-Risk, High-Reward Research program
Eight Penn scientists receive NIH grants through High-Risk, High-Reward Research program
A group of five scientists received the Transformative Research Award for a project focusing on cancer research, while three investigators received the New Innovator Award for independent projects developed by early-career investigators.
Understanding the needs of cancer care partners
Understanding the needs of cancer care partners
Through the Penn Undergraduate Research Mentoring Program, undergrads Abi Ocholi and Akin Adio deepened their understanding of qualitative research and of the experiences of caregivers.
$55M gift creates new ‘Cancer Interception’ Institute at Penn’s Basser Center for BRCA to stop hereditary cancers at the earliest stages
$55M gift creates new ‘Cancer Interception’ Institute at Penn’s Basser Center for BRCA to stop hereditary cancers at the earliest stages
Funding for the Institute from Mindy and Jon Gray will propel early detection and prevention of breast, ovarian, pancreatic, and prostate cancers.
T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response
T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response
Blocking this process, known as trogocytosis, improved the ability of a CAR T cell therapy to treat cancer in mice, according to research led by School of Veterinary Medicine scientists.
Potential new therapeutic targets to treat melanoma
Potential new therapeutic targets to treat melanoma
Penn Medicine research shows that a relative lack of DOPA, and not simply susceptibility to sun damage, helps explain why melanoma is much more common in people with light skin tones.
Losing mom to brain cancer fuels an expert’s mission for breakthrough
Losing mom to brain cancer fuels an expert’s mission for breakthrough
Research by Gregory L. Beatty, who lost his mother to glioblastoma, and colleagues have found that immunotherapy might have some activity in patients with relapsed tumors, and a potential target location for immunotherapy in glioblastoma tumors.
Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors
Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors
Biologist Wei Guo and colleagues elucidate the process of sorting and loading cargo for these biological drones with implications for a more targeted and effective use of checkpoint inhibitor drugs in cancer treatment.
In the News
Forbes
Carl June: 2024 will be seen as a breakthrough year for brain cancer
Carl June of the Perelman School of Medicine shares five insights on using CAR T cell therapy to combat cancer, featuring remarks from Bruce Levine.
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Philadelphia Inquirer
Penn plans to build a proton center for cancer treatment at Presbyterian Medical Center
Penn Medicine will build its fourth proton beam center for cancer treatment at Penn Presbyterian Medical Center in University City.
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PhillyVoice
Double mastectomies do not improve breast cancer survival likelihood for most women, study finds
Angela DeMichele of the Perelman School of Medicine says that chemotherapy and hormonal therapies are important for combating breast cancer because they’re designed to kill spreading cells.
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The New York Times
Breast cancer survival not boosted by double mastectomy, study says
Angela DeMichele of the Perelman School of Medicine comments on a study which found that breast cancer survival is not boosted by a double mastectomy.
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Today
How did Shannen Doherty die? What to know about ‘90210’ star’s cause of death
According to Penn Medicine, there is no known cure for metastatic breast cancer.
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Stat
New immunotherapy combination could ‘change the landscape’ of cancer treatment
A study by Andy Minn and postdoc Divij Mathew of the Perelman School of Medicine and colleagues found that a combination checkpoint inhibitor therapy benefited patients with lung cancer.
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