Cancer Research

Frozen testicular tissue still viable after 20 years

Many pediatric cancer treatments, though lifesaving, can compromise future fertility. In a new study in rodents, researchers from the School of Veterinary Medicine showed that testicular tissue frozen for more than 20 years could give rise to sperm.

Katherine Unger Baillie

Regulating the regulators of the immune system

Research led by School of Veterinary Medicine scientists reveals a new layer of complexity with which the immune system finds a balance between controlling pathogens and protecting healthy tissue.

Katherine Unger Baillie

Key to detecting ovarian cancer early may be in the fallopian tubes

A lack of early detection or prevention strategies for ovarian cancer is a major cause of poor outcomes for patients, and most do not have a family history or inherited genetic risk, so there is a pressing need for the development of earlier detection methods.

Caren Begun

Links between diet and cancer

Kathryn E. Wellen, an associate professor of Cancer Biology and principal investigator of the Wellen Lab, seeks answers to find the connections between metabolism and cancer biology.

From Penn Medicine News



In the News


Associated Press

A new strategy to attack aggressive brain cancer shrank tumors in two early tests

A clinical trial led by Stephen Bagley of the Perelman School of Medicine suggests that targeting two associated proteins with CAR T cell therapy could be a viable strategy for shrinking brain tumors.

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Philadelphia Inquirer

Penn’s BRCA cancer vaccine trial aims to prevent the disease in healthy people

A trial led by Susan Domchek of the Perelman School of Medicine could use a preventive vaccine to protect people with a BRCA gene mutation from cancer.

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Philadelphia Inquirer

UPenn scientists among those developing vaccines that arm the immune system to fight cancer

Penn Medicine researchers like Nobel laureate Drew Weissman are leading efforts to develop a vaccine that prevents cancer, with remarks from Susan Domchek of the Basser Center for BRCA and Robert H. Vonderheide of the Abramson Cancer Center.

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Psychology Today

AI detects cancers and immunotherapy biomarker

Daiwei Zhang and Mingyao Li of the Perelman School of Medicine and colleagues have developed an AI tool called iStar that can automatically spot tumors and types of cancer that are difficult for clinicians to see or identify and can predict candidates for immunotherapy.

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Philadelphia Inquirer

Penn started giving cancer patients free rides to appointments. It helped reduce no-shows and increase clinical trial enrollment

The Abramson Cancer Center is attempting to address one of the most common challenges cancer patients face: lack of transportation to critically important appointments. Robert Vonderheide and Carmen Guerra of the Perelman School of Medicine are quoted on the Ride Health initiative.

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Forbes

Gut health could play a role in how blood cancer patients respond to therapy

Marco Ruella of the Perelman School of Medicine says that researchers need to tackle the problems with CAR T cell therapy to increase survival rates and improve the quality of life for cancer survivors.

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