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A new technique based on special cell-penetrating peptides promises advantages over current methods for editing the genomes of primary cells, such as patients’ T cells.
Since 2017, the FDA approved more than two dozen new therapies with roots at Penn Medicine—almost half of which are first-in-class for their indications.
In a student-led effort, the School of Dental Medicine hosted the Oral Cancer Walk & 5K. The event has been an annual tradition since 2009, offering both a community celebration and a venue for discussing oral cancer prevention and detection.
Using a Penn-designed neural network called PocketMiner, a Penn Medicine research team has identified hidden protein pockets that can provide new opportunities for cancer drugs to bind to.
A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.
Since 2012, the Basser Center for BRCA at Penn Medicine’s Abramson Cancer Center has been advancing lifesaving therapies and raising awareness of the risks faced by individuals with BRCA gene mutations.
Penn researchers are developing new ways to detect and “intercept” cancer from every angle, including basic science to understand the molecular changes that lead to cancer and developing new methods for finding it.
A team of researchers led by the School of Arts & Science’s Wei Guo characterize the molecular pathways that play a major role in tumorigenesis, findings that could lead to better diagnostic tools for cancer and new targeted therapies.
When Mayassa Bou-Dargham, a postdoctoral fellow in Penn’s Abramson Family Cancer Research Institute received a pilot project grant, a banner was hung in her Lebanese hometown. Getting there took years of determination, self-confidence and, in small part, fate.
In appreciation for her cancer treatment team led by Neil Taunk, patient Dalia Jakas established a fund to empower Taunk’s research into how treatment can be improved for uterine cancers like the one she experienced.
Carl June of the Perelman School of Medicine shares five insights on using CAR T cell therapy to combat cancer, featuring remarks from Bruce Levine.
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Penn Medicine will build its fourth proton beam center for cancer treatment at Penn Presbyterian Medical Center in University City.
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Angela DeMichele of the Perelman School of Medicine says that chemotherapy and hormonal therapies are important for combating breast cancer because they’re designed to kill spreading cells.
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Angela DeMichele of the Perelman School of Medicine comments on a study which found that breast cancer survival is not boosted by a double mastectomy.
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According to Penn Medicine, there is no known cure for metastatic breast cancer.
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A study by Andy Minn and postdoc Divij Mathew of the Perelman School of Medicine and colleagues found that a combination checkpoint inhibitor therapy benefited patients with lung cancer.
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