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Cancer Research
Machine learning-triggered reminders improve end-of-life care for patients with cancer
Machine learning-triggered reminders improve end-of-life care for patients with cancer
The rates of advanced care planning conversations quadrupled, while potentially harmful therapy at end of life decreased by 25% in large randomized study.
CAR T cell therapy may eliminate tumor cells missed by surgery
CAR T cell therapy may eliminate tumor cells missed by surgery
The results of a study led by Penn Medicine’s Carl June greenlights preclinical trials for the application of CAR T therapy in gel form to surgical wounds following partial tumor removal to eliminate residual tumor cells.
The Jin Lab taps into a key cell for cancer research
The Jin Lab taps into a key cell for cancer research
The lab, led by Chengcheng Jin, an assistant professor of cancer biology and microbiology, is investigating how the immune system co-evolves with tumors during cancer progression.
FDA approves ‘glowing tumor’ imaging drug to aid lung cancer surgery
FDA approves ‘glowing tumor’ imaging drug to aid lung cancer surgery
The injectable diagnostic, Cytalux, binds to cancerous tissue and glows, making it easier for surgeons to remove tumors completely while sparing healthy tissue.
Advances in cancer research
Advances in cancer research
Recent research shows promise in a novel CAR T therapy after cancer relapse, and a novel treatment for multiple myeloma.
How the perception of risks and benefits influence cancer clinical trial withdrawal outcomes
How the perception of risks and benefits influence cancer clinical trial withdrawal outcomes
A new study from the School of Nursing examines the association between patients’ perceived benefits and burdens of research participation and withdrawal.
Study shows promise of new anti-KRAS drug for pancreatic cancer
Study shows promise of new anti-KRAS drug for pancreatic cancer
A small molecule inhibitor that attacks the difficult cancer-causing gene mutation KRAS successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer.
HPV-related cancers are on the rise in men
HPV-related cancers are on the rise in men
Recent CDC data show that roughly four of every 10 cases of HPV-induced cancer now occur in men. Penn Medicine research has found that differences in levels of a particular HPV protein may inform treatment.
CAR T cell therapy reaches beyond cancer
CAR T cell therapy reaches beyond cancer
Penn Medicine researchers laud the early results for CAR T therapy in lupus patients, which point to broader horizons for the use of personalized cellular therapies.
Home health care—a crucial edge for the future of medicine
Home health care—a crucial edge for the future of medicine
Home care has long been a part of health care, but it was the COVID-19 pandemic that led Penn Medicine to rethink who needed to be in the hospital.
In the News
Forbes
Carl June: 2024 will be seen as a breakthrough year for brain cancer
Carl June of the Perelman School of Medicine shares five insights on using CAR T cell therapy to combat cancer, featuring remarks from Bruce Levine.
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Philadelphia Inquirer
Penn plans to build a proton center for cancer treatment at Presbyterian Medical Center
Penn Medicine will build its fourth proton beam center for cancer treatment at Penn Presbyterian Medical Center in University City.
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PhillyVoice
Double mastectomies do not improve breast cancer survival likelihood for most women, study finds
Angela DeMichele of the Perelman School of Medicine says that chemotherapy and hormonal therapies are important for combating breast cancer because they’re designed to kill spreading cells.
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The New York Times
Breast cancer survival not boosted by double mastectomy, study says
Angela DeMichele of the Perelman School of Medicine comments on a study which found that breast cancer survival is not boosted by a double mastectomy.
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Today
How did Shannen Doherty die? What to know about ‘90210’ star’s cause of death
According to Penn Medicine, there is no known cure for metastatic breast cancer.
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Stat
New immunotherapy combination could ‘change the landscape’ of cancer treatment
A study by Andy Minn and postdoc Divij Mathew of the Perelman School of Medicine and colleagues found that a combination checkpoint inhibitor therapy benefited patients with lung cancer.
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