Joshua M. Liao of the Perelman School of Medicine and Mark V. Pauly of the Wharton School authored an article about how to handle large fluctuations in the price of prescription medicine.
http://www.philly.com/philly/blogs/fieldclinic/Why-drug-prices-spike-and-what-patients-can-do-about-it.html#X2MzQGvYTjARJzGq.99 Philadelphia Inquirer