John Wherry, PhD, an associate professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, and colleagues from Massachusetts General Hospital (MGH) are co-directing a $12 million grant to study immune responses in people who have been effectively cured of hepatitis C viral infection with new, high-potency antiviral drugs.

It’s a long way from DNA to RNA to protein, and only about two percent of a person’s genome is eventually converted into proteins.

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell’s energy factory. They report their findings this week in Cell.

Using powerful, newly developed cell culture and mouse  models of sporadic Parkinson’s disease (PD), a team of researchers from the Perelman School of Medicine at the University of Pennsylvania, has demonstrated that immunotherapy with specifically targeted antibodies may block the development and spread of PD pathology in the brain.

Researchers at the Center of Excellence in Environmental Toxicology (CEET), Perelman School of Medicine at the University of Pennsylvania, have been awarded a $10 million grant from the National Institute for Environmental Health Sciences (NIEHS) over the next f

It’s almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well understood.

Studies of vaccine programs in the developing world have revealed that individuals with chronic infections such as malaria and hepatitis tend to be less likely to develop the fullest possible immunity benefits from vaccines for unrelated illnesses.

Ancient philosophers looked to alchemy for clues to life everlasting. Today, researchers look to their yeast. These single-celled microbes have long served as model systems for the puzzle that is the aging process, and in this week’s issue of Cell Metabolism, they fill in yet another piece.

Four researchers from the University of Pennsylvania have been elected to the American Academy of Arts and Sciences, one of the nation's most prestigious honorary societies and a leading center for independent policy research. The new honorees are:

Three researchers from the Perelman School of Medicine at the University of Pennsylvania have been elected as new members to the American Academy of Arts and Sciences, one of the nation's most prestigious honorary societies and a leading center for independent policy research.