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Articles from Karen Kreeger
Penn Study: Targeting Downstream Proteins in Cancer-Causing Pathway Shows Promise in Cell, Animal Model

Penn Study: Targeting Downstream Proteins in Cancer-Causing Pathway Shows Promise in Cell, Animal Model

PHILADELPHIA — The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell’s powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all “hard-to-treat” cancers have a mutation in the Myc gene.

Karen Kreeger

Penn-Temple Team Discovers Gatekeeper for Maintaining Health of Cell Energy Source

Penn-Temple Team Discovers Gatekeeper for Maintaining Health of Cell Energy Source

PHILADELPHIA — Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell’s energy storehouse – the mitochondria -- is important for understanding a cell’s normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

Karen Kreeger

Institute of Medicine Elects Six New Members From Penn

Institute of Medicine Elects Six New Members From Penn

PHILADELPHIA — Six professors from the University of Pennsylvania, representing four schools, have been elected members of the Institute of Medicine (IOM), one of the nation's highest honors in biomedicine.

Katherine Unger Baillie , Karen Kreeger

Penn Study Finds Control of Pituitary Hormone Outside of Brain Has Implications for Breast Cancer

Penn Study Finds Control of Pituitary Hormone Outside of Brain Has Implications for Breast Cancer

PHILADELPHIA — The hormone prolactin is produced by the pituitary gland in the brain and then travels via the bloodstream to cells throughout the body, where it exerts multiple reproductive and metabolic effects, most notably on the breast where it is the master regulator of lactation.

Karen Kreeger

$4.6 Million Renewal from NIH to Penn Program that Aims to Diversify Biomedical Education

$4.6 Million Renewal from NIH to Penn Program that Aims to Diversify Biomedical Education

Yvonne Paterson, PhD, professor of Microbiology, at the Perelman School of Medicine, and professor and associate dean, at the School of Nursing, has been awarded an almost $5 million renewal by the National Institute for General Medical Sciences for the U

Karen Kreeger

Composite Nanofibers Developed by Penn Scientists Next Chapter in Orthopaedic Biomaterials

Composite Nanofibers Developed by Penn Scientists Next Chapter in Orthopaedic Biomaterials

Bioengineered replacements for tendons, ligaments, the meniscus of the knee, and other tissues require re-creation of the exquisite architecture of these tissues in three dimensions. These fibrous, collagen-based tissues located throughout the body have an ordered structure that gives them their robust ability to bear extreme mechanical loading.

Karen Kreeger

NIH Awards $18.5 Million to Personalized Therapeutics Consortium Led by Penn Researcher

NIH Awards $18.5 Million to Personalized Therapeutics Consortium Led by Penn Researcher

PHILADELPHIA — The National Institutes of Health's National Heart, Lung, and Blood Institute (NHLBI) awarded $18.5 million to establish the Personalized NSAID Therapeutics Consortium (PENTACON), an international group of scientists led by Garret A.

Karen Kreeger

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