Karen Kreeger

How a T cell decides to make protein X, Y, or Z can have profound effects for fighting foreign invaders or staving off dire autoimmune reactions.

Four professors from the University of Pennsylvania School of Medicine have been elected members of the Institute of Medicine (IOM), one of the nation's highest honors in biomedicine. Three of the four new inductees are women.The new members bring Penn's total to 76, out of a total active membership of 1,649.

Heart muscle cells do not normally replicate in adult tissue, but multiply with abandon during development. This is why the loss of heart muscle after a heart attack is so dire—you can’t grow enough new heart muscle to make up for the loss.

Researchers at the University of Pennsylvania School of Medicine and Immunocore Limited, Oxford, UK, today announced that a targeted agent that may have a role in treating advanced metastatic melanoma in the future has received Investigational New Drug (IND) approval and is opening enrollment for clinical trials in the UK and USA.

PHILADELPHIA - Many types of tumors grow because of over-expression or a mutation of a protein called the epidermal growth factor receptor (EGFR), normally regulated by a hormone-like peptide called the epidermal growth factor (EGF).

By comparing two species of ants, Shelley Berger, PhD, the Daniel S.

University of Pennsylvania School of Medicine researchers have described a previously unknown biological mechanism in cells that prevents them from cannibalizing themselves for fuel.

Investigators have found that fruit fly (Drosophila melanogaster) males -- in which the activity of an Alzheimer’s disease protein is reduced by 50 percent -- show impairments in learning and memory as they age.

The Pew Charitable Trusts named Zhaolan (Joe) Zhou, PhD, assistant professor of Genetics at the University of Pennsylvania School of Medicine, as a 2010 Pew Scholar in the Biomedical Sciences.

PHILADELPHIA - Using high-throughput sequencing to map the locations of a common type of jumping gene within a person’s entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic