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Articles from Steve Graff
Penn Study: Diabetes Drug Metformin with Chemo and Radiation May Improve Outcomes in Lung Cancer Patients

Penn Study: Diabetes Drug Metformin with Chemo and Radiation May Improve Outcomes in Lung Cancer Patients

Treating aggressive lung cancer with the diabetes drug metformin along with radiation and chemotherapy may slow tumor growth and recurrence, suggests new preliminary findings from researchers at the Perelman School of Medicine at the University of Pennsylvania being presented during an oral abstract session October 28 at the 15th World Conference on Lung

Steve Graff

Penn Study: Visits to Multiple HIV Clinics Linked to Poorer Outcomes

Penn Study: Visits to Multiple HIV Clinics Linked to Poorer Outcomes

Patients who received care at multiple HIV clinics—as opposed to only one— were less likely to take their medication and had higher HIV viral loads,  a new study published in the journal AIDS and Behavior of almost 13,000 HIV patients in Philadelphia from Penn Medicine found.  The findings reinforce t

Steve Graff

When ICUs Get Busy, Doctors Triage Patients More Efficiently, Penn Study finds

When ICUs Get Busy, Doctors Triage Patients More Efficiently, Penn Study finds

A new study by Penn Medicine researchers published Oct. 1 in the Annals of Internal Medicine found that busy intensive care units (ICUs) discharge patients more quickly than they otherwise would and do so without adversely affecting patient outcomes – suggesting that low-value extensions of ICU stays are minimized during times of increased ICU capacity strain.

Steve Graff

Penn Study: Shutting off Neurons Helps Bullied Mice Overcome Symptoms of Depression

Penn Study: Shutting off Neurons Helps Bullied Mice Overcome Symptoms of Depression

A new drug target to treat depression and other mood disorders may lie in a group of GABA neurons (gamma-aminobutyric acid –the neurotransmitters which inhibit other cells) shown to contribute to symptoms like social withdrawal and increased anxiety, Penn Medicine researchers report in a new study in the Journal of Neuroscience.  

Steve Graff

Weight Loss Drug Helps Curb Cocaine Addictions, Penn Study Finds

Weight Loss Drug Helps Curb Cocaine Addictions, Penn Study Finds

The drug topiramate, typically used to treat epilepsy and more recently weight loss, may also help people addicted to both cocaine and alcohol use less cocaine, particularly heavy users, researchers in the department of Psychiatry at Penn Medicine report in a new study published in Drug and

Steve Graff

Penn: Path of Plaque Buildup in Brain Shows Promise as Early Biomarker for Alzheimer's Disease

Penn: Path of Plaque Buildup in Brain Shows Promise as Early Biomarker for Alzheimer's Disease

The trajectory of amyloid plaque buildup—clumps of abnormal proteins in the brain linked to Alzheimer’s disease—may serve as a more powerful biomarker for early detection of cognitive decline rather than using the total amount to gauge risk, researchers from Penn Medicine’s Department of Radiology suggest in a new study published online July 1

Steve Graff

Penn: Potentially Life-Saving Cooling Treatment Rarely Used for Cardiac Arrests

Penn: Potentially Life-Saving Cooling Treatment Rarely Used for Cardiac Arrests

The brain-preserving cooling treatment known as therapeutic hypothermia is rarely being used in patients who suffer cardiac arrest while in the hospital, despite its proven potential to improve survival and neurological function, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the June issue of Critical Care Medicine. 

Steve Graff

Penn Study Finds Stressed Dads Can Affect Offspring Brain Development

Penn Study Finds Stressed Dads Can Affect Offspring Brain Development

Sperm doesn’t appear to forget anything. Stress felt by dad—whether as a preadolescent or adult—leaves a lasting impression on his sperm that gives sons and daughters a blunted reaction to stress, a response linked to several mental disorders. 

Steve Graff

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