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Articles from Steve Graff
Sharp, Sustained Increases in Suicides Closely Shadowed Austerity Events in Greece, Penn Study Finds

Sharp, Sustained Increases in Suicides Closely Shadowed Austerity Events in Greece, Penn Study Finds

Sharp and significant increases in suicides followed select financial crisis events and austerity announcements in Greece, from the start of the country’s 2008 recession to steep spending cuts in 2012, Penn Medicine researchers report in a new study published online this week in the British  Medical Journal Open, along with colleagues from Greece and the United Kingdom.

Steve Graff

Life at Higher Elevation Linked to Lower Incidence of Lung Cancer, Penn Study Suggests

Life at Higher Elevation Linked to Lower Incidence of Lung Cancer, Penn Study Suggests

Here’s another potential reason to live up in the mountains. Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania.

Steve Graff

Patch or Pills? How Quickly Smokers Metabolize Nicotine May Point to Most Effective Way to Quit, Penn Study Finds

Patch or Pills? How Quickly Smokers Metabolize Nicotine May Point to Most Effective Way to Quit, Penn Study Finds

Nearly 70 percent of smokers who try to quit relapse within one week – daunting odds for people trying to kick the habit. Researchers have long theorized that some individuals may be genetically programmed to have an easier time than others, but with few clues about why, experts have been unable to guide smokers looking to quit toward a strategy – the nicotine patch versus prescription pills, for instance – with the best chance of success.

Steve Graff

Penn Study: Overly Conservative FDA Label Likely Prevents Use of Metformin in Many Type 2 Diabetics

Penn Study: Overly Conservative FDA Label Likely Prevents Use of Metformin in Many Type 2 Diabetics

Many patients with type 2 diabetes in the United States may be discouraged from taking metformin—a proven, oral diabetes medicine—because the U.S. Food and Drug Administration inappropriately labels the drug unsafe for some patients also suffering from kidney problems, researchers from Penn Medicine and Weill Cornel Medical College report this week in a research letter published in JAMA Internal Medicine.

Steve Graff

Penn Study: Majority of Women with Early-Stage Breast Cancer in U.S. Receive Unnecessarily Long Courses of Radiation

Penn Study: Majority of Women with Early-Stage Breast Cancer in U.S. Receive Unnecessarily Long Courses of Radiation

Two-thirds of women treated for early-stage breast cancer in the U.S. receive longer radiation therapy than necessary, according to a new study published in JAMA this week from Penn Medicineresearchers Ezekiel J. Emanuel, MD, PhD, and Justin E. Bekelman, MD.

Steve Graff

Brain Activity after Smokers Quit Predicts Chances of Relapsing, Penn Medicine Study Suggests

Brain Activity after Smokers Quit Predicts Chances of Relapsing, Penn Medicine Study Suggests

Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again—a prediction that goes above and beyond today’s clinical or behavioral tools for assessing relapse risk.

Steve Graff

Penn Medicine receives $3.5M NCI grant to study cervical cancer in HIV positive women in Botswana

Penn Medicine receives $3.5M NCI grant to study cervical cancer in HIV positive women in Botswana

The introduction of antiretroviral drugs in Botswana over the last two decades has increased the life expectancies of people living with HIV—many of whom are women co-infected with the  human papillomavirus virus (HPV)—considerably: from 39 years to the low 60s.  As a result, this co-infected group of women is at a much higher risk of developing HPV-associated cervical cancer.

Steve Graff

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