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Penn Medicine's New Immunotherapy Study Will Pit PD-1 Inhibitor Against Advanced Lung Cancer
Penn Medicine researchers have begun a new immunotherapy trial with the “checkpoint inhibitor” known as pembrolizumab in patients with oligometastatic lung cancer—a state characterized by a few metastases in a confined area—who have completed conventional treatments and are considered free of active disease but remain at a high risk for recurrence.
Life at Higher Elevation Linked to Lower Incidence of Lung Cancer, Penn Study Suggests
Here’s another potential reason to live up in the mountains. Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania.
Patch or Pills? How Quickly Smokers Metabolize Nicotine May Point to Most Effective Way to Quit, Penn Study Finds
Nearly 70 percent of smokers who try to quit relapse within one week – daunting odds for people trying to kick the habit. Researchers have long theorized that some individuals may be genetically programmed to have an easier time than others, but with few clues about why, experts have been unable to guide smokers looking to quit toward a strategy – the nicotine patch versus prescription pills, for instance – with the best chance of success.
Penn Study: Radiation Plus Hormone Therapy Prolongs Survival for Older Men with Prostate Cancer
Adding radiation treatment to hormone therapy saves more lives among older men with locally advanced prostate therapy than hormone therapy alone, according to a new study in the Journal of Clinical Oncology this week from Penn Medicine researchers.
Penn Study: Overly Conservative FDA Label Likely Prevents Use of Metformin in Many Type 2 Diabetics
Many patients with type 2 diabetes in the United States may be discouraged from taking metformin—a proven, oral diabetes medicine—because the U.S. Food and Drug Administration inappropriately labels the drug unsafe for some patients also suffering from kidney problems, researchers from Penn Medicine and Weill Cornel Medical College report this week in a research letter published in JAMA Internal Medicine.
Penn Study: Majority of Women with Early-Stage Breast Cancer in U.S. Receive Unnecessarily Long Courses of Radiation
Two-thirds of women treated for early-stage breast cancer in the U.S. receive longer radiation therapy than necessary, according to a new study published in JAMA this week from Penn Medicineresearchers Ezekiel J. Emanuel, MD, PhD, and Justin E. Bekelman, MD.
People with Mental Illness More Likely To Be Tested for HIV, Penn Medicine Study Finds
People with mental illness are more likely to have been tested for HIV than those without mental illness, according to a new study from a team of researchers at Penn Medicine&nb
Brain Activity after Smokers Quit Predicts Chances of Relapsing, Penn Medicine Study Suggests
Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again—a prediction that goes above and beyond today’s clinical or behavioral tools for assessing relapse risk.
Penn Study Shows Bed Bugs Can Transmit Parasite that Causes Chagas Disease
The bed bug may be just as dangerous as its sinister cousin, the triatomine, or “kissing” bug.
Penn Medicine receives $3.5M NCI grant to study cervical cancer in HIV positive women in Botswana
The introduction of antiretroviral drugs in Botswana over the last two decades has increased the life expectancies of people living with HIV—many of whom are women co-infected with the human papillomavirus virus (HPV)—considerably: from 39 years to the low 60s. As a result, this co-infected group of women is at a much higher risk of developing HPV-associated cervical cancer.