Through
11/26
Perelman School of Medicine
Quieting Cells' Low-Oxygen Alarm Stops Flare-ups in Rare Bone Disorder, Penn Animal Study Finds
The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms.
Penn/Vanderbilt Study: Genetic Risk Factors of Disparate Diseases Share Similar Biological Underpinnings
The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsylvania, the University of Arizona Health Sciences
Penn Institute for Biomedical Informatics and colleagues Identify "Roadmap" of Disease Mechanisms to Identify Candidate Drug Targets
The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsyl
Penn Study: A Long-noncoding RNA Regulates Repair of DNA Breaks in Triple-Negative Breast Cancer Cells
The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes – less than 2 percent of the total – but 70 percent of the genome is made into non-gene-encoding RNA.
Penn Medicine Study Uncovers New Pathways that Control Skin Tanning and Lightening
When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.
Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis
About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous studie
Penn Study Suggests Changes in Skin "Microbiome" During Canine Atopic Dermatitis Could Lead to Antibiotic-Free Therapies for Human and Canine Disease
Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.
Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk, Penn Study Suggests
Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient’s risk of colorectal cancer, suggests a new, large case-control study from Penn Medicine researchers published this week in&
Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis
About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous studie
Two Penn Medicine Physicians Elected to Association of American Physicians
Two Penn Medicine physicians – Ebbing Lautenbach, MD, MPH, MSCE, chief of the division of Infectious Diseases and the Robert Austrian Professor in the department of Medicine, and Ben Z.
In the News
Philadelphia Inquirer
Is there a chemical link to memory loss? Penn researchers get $11M to study dementia causes
The National Institutes of Health have awarded $11 million to Aimin Chen of the Perelman School of Medicine to study the link between chemical exposures and dementia.
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Philadelphia Inquirer
COVID patient who survived coma reunites with Penn care team
A COVID patient who survived his coma recently reunited with the Penn Medicine care team that helped save his life, including Jennifer Olenik of the Perelman School of Medicine.
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CNN
Vaping immediately affects vascular health and oxygen levels, study shows, even without nicotine
Research published by Marianne Nabbout while a resident at the Perelman School of Medicine finds that vaping has an immediate effect on blood vessels even if an e-cigarette doesn’t contain nicotine.
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Fox 29 (Philadelphia)
Former patient gives thanks to PA hospital staff after surviving coma, COVID-19 battle
A former COVID patient who spent six months in a coma returned to thank the Penn Medicine team that contributed to his survival, including Megan Carr-Lettieri.
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Forbes
Insomnia may be more common than you think. Here’s what to know
According to Penn Medicine, about 1 in 4 Americans experiences difficulty with sleep each year.
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